ArticleAngewandte Chemie (International ed. in English)2014
A biocompatible alkene hydrogenation merges organic synthesis with microbial metabolism.
Article in Angewandte Chemie (International ed. in English), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Native HNature chemistry · 2026Article
- Concatenating Microbial, Enzymatic, and Organometallic Catalysis for Integrated Conversion of Renewable Carbon Sources.JACS Au · 2024Review
- Microbial Upcycling of Waste PET to Adipic Acid.ACS central science · 2023Article
- In Vivo Biocatalytic Cascades Featuring an Artificial-Enzyme-Catalysed New-to-Nature Reaction.Angewandte Chemie (International ed. in English) · 2023Article
- Palladium Nanoparticles fromJACS Au · 2022Article
- Article
- Extracellular Electron Transfer Enables Cellular Control of Cu(I)-Catalyzed Alkyne-Azide Cycloaddition.ACS central science · 2022Article
- Activation of C-O and C-N Bonds Using Non-Precious-Metal Catalysis.ACS catalysis · 2020Article
- Cycloisomerization of Olefins in Water.Angewandte Chemie (International ed. in English) · 2020Article
- A Screening Platform to Identify and Tailor Biocompatible Small-Molecule Catalysts.Chemistry (Weinheim an der Bergstrasse, Germany) · 2019Article
- Chemoenzymatic conversion of amides to enantioenriched alcohols in aqueous medium.Communications chemistry · 2019Article
- Article
- Alkene hydrogenation activity of enoate reductases for an environmentally benign biosynthesis of adipic acid.Chemical science · 2017Article
- Multicatalytic, Light-Driven Upgrading of Butanol to 2-Ethylhexenal and Hydrogen under Mild Aqueous Conditions.ACS catalysis · 2017Article
- Conversion of Ethanol to 2-Ethylhexenal at Ambient Conditions Using Tandem, Biphasic Catalysis.ACS sustainable chemistry & engineering · 2017Article
- Catalytic Upgrading in Bacteria-Compatible Conditions via a Biocompatible Aldol Condensation.ACS sustainable chemistry & engineering · 2016Article
- Hybrid bioinorganic approach to solar-to-chemical conversion.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Interfacing microbial styrene production with a biocompatible cyclopropanation reaction.Angewandte Chemie (International ed. in English) · 2015Article
- Using non-enzymatic chemistry to influence microbial metabolism.Current opinion in chemical biology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Organic chemists and metabolic engineers use orthogonal technologies to construct essential small molecules such as pharmaceuticals and commodity chemicals. While chemists have leveraged the unique capabilities of biological catalysts for small-molecule production, metabolic engineers have not likewise integrated reactions from organic synthesis with the metabolism of living organisms. Reported herein is a method for alkene hydrogenation which utilizes a palladium catalyst and hydrogen gas generated directly by a living microorganism. This biocompatible transformation, which requires both catalyst and microbe, and can be used on a preparative scale, represents a new strategy for chemical synthesis that combines organic chemistry and metabolic engineering.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.