Trial reportJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2014
Effectiveness of intraoperative cholangiography using indocyanine green (versus contrast fluid) for the correct assessment of extrahepatic bile ducts during day-case laparoscopic cholecystectomy.
Trial report in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 6 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 6 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Intraoperative imaging of the common bile duct: a systematic review.Surgical endoscopy · 2025Pooled it
- 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy.World journal of emergency surgery : WJES · 2021Guideline
- Comparison of indocyanine green dye fluorescent cholangiography with intra-operative cholangiography in laparoscopic cholecystectomy: a meta-analysis.Surgical endoscopy · 2021Pooled it
- Safe cholecystectomy multi-society practice guideline and state-of-the-art consensus conference on prevention of bile duct injury during cholecystectomy.Surgical endoscopy · 2020Guideline
- Optimizing the image of fluorescence cholangiography using ICG: a systematic review and ex vivo experiments.Surgical endoscopy · 2018Pooled it
- Biliary tract visualization using near-infrared imaging with indocyanine green during laparoscopic cholecystectomy: results of a systematic review.Surgical endoscopy · 2017Pooled it
- The Best Approach for Laparoscopic Fluorescence Cholangiography: Overview of the Literature and Optimization of Dose and Dosing Time.Surgical innovation · 2017Trial
- Is intraoperative cholangiography necessary during laparoscopic cholecystectomy for cholelithiasis?World journal of gastroenterology · 2015Trial
- Indocyanine green fluorescence improves safety in laparoscopic cholecystectomy using the Fundus First technique: a retrospective study.Frontiers in surgery · 2025Article
- Feasibility of Indocyanine Green Fluorescent Cholangiography Via Inguinal Nodal Injection Approach in Upper Gastrointestinal Oncological Surgeries. A Pilot Study.Indian journal of surgical oncology · 2024Article
- Near-infrared indocyanine green fluorescent cholangiography in urgent and emergency laparoscopic cholecystectomy: a preliminary study after propensity score-matched study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Near infrared indocyanine green fluorescent cholangiography versus intraoperative cholangiography to improve safety in laparoscopic cholecystectomy for gallstone disease-a systematic review protocol.Systematic reviews · 2022Article
- Application of near-infrared fluorescent cholangiography using indocyanine green in laparoscopic cholecystectomy.The Journal of international medical research · 2020Article
- Fluorescence-guided hepatobiliary surgery with long and short wavelength fluorophores.Hepatobiliary surgery and nutrition · 2020Review
- A practical guide for the use of indocyanine green and methylene blue in fluorescence-guided abdominal surgery.Journal of surgical oncology · 2018Review
- Near-infrared cholecystocholangiography with direct intragallbladder indocyanine green injection: preliminary clinical results.Surgical endoscopy · 2018Article
- Fluorescent Imaging With Indocyanine Green During Laparoscopic Cholecystectomy in Patients at Increased Risk of Bile Duct Injury.Surgical innovation · 2017Article
- Treatment of choledochal cyst in a pediatric population. A single institution experience of 15-years. Case series.Annals of medicine and surgery (2012) · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDuring cholecystectomy, intraoperative cholangiography using contrast fluid (IOC-CF) is still the "gold standard" for biliary tract identification but has many associated pitfalls. A new IOC technique using indocyanine green (IOC-IG) appears to be promising. Here, we studied the effectiveness of IOC-IG (vs IOC-CF) during day-case laparoscopic cholecystectomy. MATERIALS AND
methodsOver a 6-month period, we included 23 patients (with no cirrhosis or risk factors for choledocholithiasis) scheduled for day-case laparoscopic cholecystectomy. The primary efficacy criterion was the "analyzability rate" (i.e., the ability to identify the cystic duct, the cystic duct-hepatic duct junction, and the common bile duct) for the IOC-CF and IOC-IG procedures after dissection. Indocyanine green was infused under general anesthesia. The same near-infrared laparoscopic imaging system was used for IOC-IG and conventional visual inspection. IOC-CF was always attempted after dissection. Each patient served as his/her own control. Cholecystectomies were video-recorded for subsequent off-line, blind analysis.
resultsThe analyzability rate was 74 % for IOC-IG after dissection, 70 % for IOC-CF (p = 0.03), 26 % for conventional visual inspection, and 48 % for IOC-IG before dissection. When each IOC modality (conventional visual inspection, IOC-IG before and after dissection) was considered as a diagnostic test, the accuracy for simultaneous identification of the three anatomic elements was respectively 48, 52, and 74 %. No adverse events occurred during the IOC-IG procedure.
conclusionIOC-IG was feasible and safe. Our results suggest that this technique is more effective than IOC-CF for biliary tract identification after dissection and may constitute a powerful diagnostic test for the detection of extrahepatic ducts.
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