ArticleeLife2014
Caenorhabditis elegans male sensory-motor neurons and dopaminergic support cells couple ejaculation and post-ejaculatory behaviors.
Article in eLife, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed, 55 citations in OpenAlex.
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- Single-nucleus neuronal transcriptional profiling of male C. elegans uncovers regulators of sex-specific and sex-shared behaviors.Cell reports · 2025Article
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- C. elegans males optimize mate-preference decisions via sex-specific responses to multimodal sensory cues.Current biology : CB · 2024Article
- Unraveling the hierarchical structure of posture and muscle activity changes during mating ofPNAS nexus · 2024Article
- Glia in Invertebrate Models: Insights from Caenorhabditis elegans.Advances in neurobiology · 2024Review
- Regulation and modulation of biogenic amine neurotransmission inFrontiers in physiology · 2023Review
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- Neuropeptide signalling shapes feeding and reproductive behaviours in maleLife science alliance · 2022Article
- Virus infection modulates male sexual behaviour in Caenorhabditis elegans.Molecular ecology · 2021Article
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- Neuropeptides and Behaviors: How Small Peptides Regulate Nervous System Function and Behavioral Outputs.Frontiers in molecular neuroscience · 2021Review
- The connectome of the Caenorhabditis elegans pharynx.The Journal of comparative neurology · 2020Article
- Succinate Dehydrogenase-Regulated Phosphoenolpyruvate Carboxykinase Sustains Copulation Fitness in Aging C. elegans Males.iScience · 2020Article
- Sexually Dimorphic Regulation of Behavioral States by Dopamine inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Sexual Dimorphism and Sex Differences inGenetics · 2018Article
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4 authors at 2 institutions in 1 country.
Funding
Abstract
The circuit structure and function underlying post-coital male behaviors remain poorly understood. Using mutant analysis, laser ablation, optogenetics, and Ca2+ imaging, we observed that following C. elegans male copulation, the duration of post-coital lethargy is coupled to cellular events involved in ejaculation. We show that the SPV and SPD spicule-associated sensory neurons and the spicule socket neuronal support cells function with intromission circuit components, including the cholinergic SPC and PCB and the glutamatergic PCA sensory-motor neurons, to coordinate sex muscle contractions with initiation and continuation of sperm movement. Our observations suggest that the SPV and SPD and their associated dopamine-containing socket cells sense the intrauterine environment through cellular endings exposed at the spicule tips and regulate both sperm release into the hermaphrodite and the recovery from post-coital lethargy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.