Evidence map›Paper›PMID 24915445›Full record

ArticlePLoS biology2014

Key applications of plant metabolic engineering.

Warren Lau, Michael A Fischbach, Anne Osbourn, Elizabeth S Sattely

Abstract read
In one paragraph

Article in PLoS biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Evolutionary trajectory of transcription factors and selection of targets for metabolic engineering.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Synthetic biology for pharmaceutical drug discovery.Drug design, development and therapy · 2015
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Warren LauDepartment of Chemical Engineering, Stanford University, Stanford, California, United States of America.
Michael A FischbachDepartment of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, United States of America.
Anne OsbournDepartment of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich United Kingdom.
Elizabeth S SattelyDepartment of Chemical Engineering, Stanford University, Stanford, California, United States of America.

Funding

Identifying and characterizing small molecules from the human microbiomeDP2OD007290 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FISCHBACH, MICHAEL ANDREW · 2010 to 2010
$2.3M
Biosynthesis of Indolic Phytoalexins: Mechanisms of Plant Innate Immune ResponseR00GM089985 · NIGMS · STANFORD UNIVERSITY · PI SATTELY, ELIZABETH SUSAN · 2011 to 2013
$738k
Biosynthesis of Indolic Phytoalexins: Mechanisms of Plant Innate Immune ResponseK99GM089985 · NIGMS · HARVARD MEDICAL SCHOOL · PI SATTELY, ELIZABETH SUSAN · 2010 to 2010
$90k
Biotechnology and Biological Sciences Research Council BBS/E/J/00000614NIGMS NIH HHS GM089985NIGMS NIH HHS K99 GM089985NIGMS NIH HHS R00 GM089985NIH HHS DP2 OD007290NIH HHS OD007290
6 · The paper itself

Abstract

Great strides have been made in plant metabolic engineering over the last two decades, with notable success stories including Golden rice. Here, we discuss the field's progress in addressing four long-standing challenges: creating plants that satisfy their own nitrogen requirement, so reducing or eliminating the need for nitrogen fertilizer; enhancing the nutrient content of crop plants; engineering biofuel feed stocks that harbor easy-to-access fermentable saccharides by incorporating self-destructing lignin; and increasing photosynthetic efficiency. We also look to the future at emerging areas of research in this field.

Indexed as

Metabolic EngineeringBiofuelsCrops, AgriculturalNitrogen FixationPhotosynthesisBiofuels

Identifiers

PMID24915445
PMCPMC4051588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.