ArticlePloS one2014
Image quality and radiation dose of lower extremity CT angiography using 70 kVp, high pitch acquisition and sinogram-affirmed iterative reconstruction.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Halved contrast medium dose in lower limb dual-energy computed tomography angiography-a randomized controlled trial.European radiology · 2023Trial
- Radiation dose and image quality with new protocol in lower extremity computed tomography angiography.La Radiologia medica · 2019Trial
- Radiation dose and image quality of 70 kVp cerebral CT angiography with optimized sinogram-affirmed iterative reconstruction: comparison with 120 kVp cerebral CT angiography.European radiology · 2015Trial
- Lower-Extremity CT Angiography: Inter-Hospital Dose Variability and Protocol Optimization in Sudan.Cureus · 2026Article
- Patient-Specific Cutting Guides for Alignment-Correcting Osteotomy About the Knee: A Study of Accuracy, Cost, and Surgical and Fluoroscopic Safety.Orthopaedic journal of sports medicine · 2025Article
- Optimizing low contrast volume thoracic CT angiography: From the basics to the advanced.Journal of clinical imaging science · 2022Article
- Lower extremity CT angiography in peripheral arterial disease: from the established approach to evolving technical developments.The international journal of cardiovascular imaging · 2021Review
- Feasibility of low-dose contrast media in run-off CT angiography on dual-layer spectral detector CT.Quantitative imaging in medicine and surgery · 2021Article
- Quick evaluation of lower leg ischemia in patients with peripheral arterial disease by time maximum intensity projection CT angiography: a pilot study.BMC medical imaging · 2021Article
- CT Angiography in the Lower Extremity Peripheral Artery Disease Feasibility of an Ultra-Low Volume Contrast Media Protocol.Cardiovascular and interventional radiology · 2018Article
- Patient radiation biological risk in computed tomography angiography procedure.Saudi journal of biological sciences · 2017Article
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Abstract
objectivesThe purpose of this study was to assess image quality and radiation dose of lower extremity CT angiography (CTA) with 70 kVp, high pitch acquisition and sinogram-affirmed iterative reconstruction (SAFIRE).
methodsLower extremity CTAs were performed on 44 patients: 22 patients were examined using protocol A (120 kVp, pitch of 0.85 and 120 ml of contrast agent on a first-generation dual-source CT) (120 kVp group) and 22 patients were evaluated with protocol B (70 kVp, pitch of 2.2 and 80 ml of contrast agent on a second-generation dual-source CT) (70 kVp group). Images from the 120 kVp group were reconstructed with filtered back projection (FBP) and images from the 70 kVp group with SAFIRE. The attenuation, image noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Two radiologists subjectively assessed image quality of lower extremity arteries, plantar arterial enhancement and venous contamination of all patients. Radiation dose was compared between the two groups.
resultsHigher mean intravascular attenuation was obtained in the 70 kVp group (70 vs. 120 kVp group, 555.4 ± 83.4 HU vs. 300.9 ± 81.4 HU, P<0.001), as well as image noise (20.0 ± 2.8 HU vs. 17.5 ± 3.2 HU, P = 0.010), SNR (32.0 ± 7.0 vs. 19.1 ± 6.9, P<0.001) and CNR (28.1 ± 6.6 vs 15.9 ± 6.3, P<0.001). No difference in subjective image quality and plantar arterial enhancement was found between 120 kVp group and 70 kVp group (all P>0.05). The venous contamination score was 1.5 ± 0.8 for 120 kVp group while no venous contamination was found in 70 kVp group. The inter-observer agreement was moderate to good for both groups (0.515∼1, P<0.001). The effective dose was lower in 70 kVp group (0.3 ± 0.1 mSv) than in 120 kVp group (1.6 ± 0.7 mSv)(P<0.001).
conclusionsLower extremity CTA using 70 kVp, high pitch acquisition and SAFIRE, except increasing imaging noise, allows for lower radiation dose and contrast material volume without compromising image quality.
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