Evidence map›Paper›PMID 24915143›Full record

ReviewPharmacogenetics and genomics2014

PharmGKB summary: uric acid-lowering drugs pathway, pharmacodynamics.

Ellen M McDonagh, Caroline F Thorn, John T Callaghan, Russ B Altman, Teri E Klein

Registry-linked trialAbstract readReview
In one paragraph

Review in Pharmacogenetics and genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05414669 (The Effect of Allopurinol on Malondialdehyde, Nitric Oxide, Kidney Injury Molecule-1 Urine Levels, Resistive Index and Renal Elastography in Kidney Stone Patients After Extra Corporeal Shockwave Lithotripsy), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05414669 phase4completednot on this mapstarted 2020, after this paper: background citation

The Effect of Allopurinol on Malondialdehyde, Nitric Oxide, Kidney Injury Molecule-1 Urine Levels, Resistive Index and Renal Elastography in Kidney Stone Patients After Extra Corporeal Shockwave Lithotripsy

TypeinterventionalSponsorRSUP Prof. Dr. I.G.N.G. NgoerahalRan2020 to 2021Enrolled35ConditionsKidney CalculiArmsAllopurinol Tablet 300 mg, Control Group
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Article
  4. Review
  5. Article
  6. Review
  7. Renal effects of uric acid: hyperuricemia and hypouricemia.The Korean journal of internal medicine · 2020
    Review
  8. Article
  9. Uric Acid and Arterial Stiffness.Therapeutics and clinical risk management · 2020
    Review
  10. Review
  11. Effects ofEvidence-based complementary and alternative medicine : eCAM · 2019
    Article
  12. Review
  13. Review
  14. Uric Acid and Neurocognitive Function in Survivors of Childhood Acute Lymphoblastic Leukemia Treated with Chemotherapy Only.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ellen M McDonaghDepartments of aGenetics bBioengineering, Stanford University, Stanford, California cACOS for Research, Department of Veterans Affairs Medical Center Departments of dMedicine ePharmacology/Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Caroline F Thorn
John T Callaghan
Russ B Altman
Teri E Klein

Funding

PharmGKB: pharmacogenomics knowledge for precision medicineR24GM061374 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO, KLEIN, TERI ELLEN · 2010 to 2018
$25.2M
NIGMS NIH HHS R24 GM061374NIGMS NIH HHS R24 GM61374
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression RegulationGenetic VariationGout SuppressantsHumansUric AcidGout SuppressantsUric Acid

Identifiers

PMID24915143
PMCPMC4122637

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.