Evidence map›Paper›PMID 24914557›Full record

ArticleDevelopmental cell2014

Directing traffic and autophagy in axonal transport.

Peter J Hollenbeck

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Developmental cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Autophagy Dysfunction in ALS: from Transport to Protein Degradation.Journal of molecular neuroscience : MN · 2022
    Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Peter J HollenbeckDepartment of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA. Electronic address: phollenb@purdue.edu.

Funding

CONTROL OF NEURONAL ORGANELLE TRANSPORTR01NS027073 · NINDS · PURDUE UNIVERSITY WEST LAFAYETTE · PI HOLLENBECK, PETER J. · 1990 to 2013
$3.6M
NINDS NIH HHS R01 NS027073
6 · The paper itself

Abstract

In this issue of Developmental Cell, Fu et al. (2014) address what determines persistent directional movement along microtubules of organelles capable of bidirectional transit. They show that retrograde axonal autophagosome transport is mediated by the scaffolding protein JIP1, which not only inhibits anterograde movement but may also promote autophagosome maturation.

Indexed as

PhagosomesAdaptor Proteins, Signal TransducingAnimalsAutophagyAxonal TransportDyneinsKinesinsMicrotubule-Associated ProteinsAdaptor Proteins, Signal TransducingDyneinsKinesinsMap1lc3b protein, mouseMapk8ip protein, mouseMicrotubule-Associated Proteins

Identifiers

PMID24914557
PMCPMC4106466

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.