ArticleWorld journal of gastroenterology2014
Changes in intestinal microflora in rats with acute respiratory distress syndrome.
Article in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 25 citations in OpenAlex.
- A mini-review of the relationship between intestinal microecology and acute respiratory distress syndrome.PeerJ · 2025Review
- Hydroxychloroquine attenuates sepsis-induced acute respiratory distress syndrome in rats.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024Article
- The causal relationship between gut microbiota and diabetic neuropathy: a bi-directional two-sample Mendelian randomization study.Frontiers in endocrinology · 2024Article
- Article
- Fecal microbiota transplantation from HUC-MSC-treated mice alleviates acute lung injury in mice through anti-inflammation and gut microbiota modulation.Frontiers in microbiology · 2023Article
- A High-Fiber Diet or Dietary Supplementation of Acetate Attenuate Hyperoxia-Induced Acute Lung Injury.Nutrients · 2022Article
- Camels' biological fluids contained nanobodies: promising avenue in cancer therapy.Cancer cell international · 2022Review
- Herbal medicine in the treatment of COVID-19 based on the gut-lung axis.Acupuncture and herbal medicine · 2022Review
- Rhubarb Alleviates Acute Lung Injury by Modulating Gut Microbiota Dysbiosis in Mice.Current microbiology · 2022Article
- Immunosuppressive effect of mesenchymal stem cells on lung and gut CD8Cell proliferation · 2021Article
- Review
- Herbal Medicine, Gut Microbiota, and COVID-19.Frontiers in pharmacology · 2021Review
- Impact of fecal microbiota transplantation on TGF-β1/Smads/ERK signaling pathway of endotoxic acute lung injury in rats.3 Biotech · 2020Article
- Houttuynia cordata polysaccharide alleviated intestinal injury and modulated intestinal microbiota in H1N1 virus infected mice.Chinese journal of natural medicines · 2019Article
- Effects of3 Biotech · 2017Article
- Changes in intestinal microflora of Caenorhabditis elegans following Bacillus nematocida B16 infection.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo implement high-throughput 16S rDNA sequencing to study microbial diversity in the fecal matter of rats with acute lung injury/acute respiratory distress syndrome (ALI/ARDS).
methodsIntratracheal instillation of lipopolysaccharide was used to induce ALI, and the pathological changes in the lungs and intestines were observed. D-lactate levels and diamine oxidase (DAO) activities were determined by enzymatic spectrophotometry. The fragments encompassing V4 16S rDNA hypervariable regions were PCR amplified from fecal samples, and the PCR products of V4 were sequenced by Illumina MiSeq.
resultsIncreased D-lactate levels and DAO activities were observed in the model group (P < 0.01). Sequencing results revealed the presence of 3780 and 4142 species in the control and model groups, respectively. The percentage of shared species was 18.8419%. Compared with the control group, the model group had a higher diversity index and a lower number of species of Fusobacteria (at the phylum level), Helicobacter and Roseburia (at the genus level) (P < 0.01). Differences in species diversity, structure, distribution and composition were found between the control group and early ARDS group.
conclusionThe detection of specific bacteria allows early detection and diagnosis of ALI/ARDS.
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