Evidence map›Paper›PMID 24914317›Full record

ReviewWorld journal of gastroenterology2014

Helicobacter pylori: a chameleon-like approach to life.

Luigina Cellini

Open access · bronzeAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. BeyondMedicina (Kaunas, Lithuania) · 2025
    Review
  3. On the Role of Food in the Transmission ofFoods (Basel, Switzerland) · 2025
    Review
  4. Diseases (Basel, Switzerland) · 2024
    Review
  5. Article
  6. [Construction and characterization of aNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  7. A review for non-antibiotic treatment ofFrontiers in microbiology · 2024
    Review
  8. Article
  9. Helicobacter pylori: an up-to-date overview on the virulence and pathogenesis mechanisms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Review
  10. Immunometabolism in biofilm infection: lessons from cancer.Molecular medicine (Cambridge, Mass.) · 2022
    Review
  11. Article
  12. Article
  13. Searching for New Tools to Counteract theAntibiotics (Basel, Switzerland) · 2020
    Article
  14. A peptide of a type I toxin-antitoxin system inducesProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. World journal of gastroenterology · 2018
    Review
  19. Article
  20. Structure of Csd3 from Helicobacter pylori, a cell shape-determining metallopeptidase.Acta crystallographica. Section D, Biological crystallography · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Luigina CelliniLuigina Cellini, Department of Pharmacy, University "G. d'Annunzio" Chieti-Pescara, 66100 Chieti, Italy.
University of Chieti-Pescara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori (H. pylori) is widely adaptable for colonization in human stomachs in more than half of the world's population. The microorganism is characterized by an unusual capability of arranging itself in both genotypic and phenotypic ways. Stressing conditions, including antimicrobial agents in sub-inhibitory concentrations, facilitate entering the viable but nonculturable state in which bacterial cells acquire the coccoid form. This morphotype represents an important strategy for bacterial survival in unsuitable conditions and also allows escape from the immune system. H. pylori is capable of forming biofilm outside and inside the host. For the bacterial population, the sessile growth mode represents an ideal environment for gene rearrangement, as it allows the acquiring of important tools aimed to improve bacterial "fitness" and species preservation. Biofilm formation in H. pylori in the human host also leads to recalcitrance to antibiotic treatment, thus hampering eradication. These lifestyle changes of H. pylori allow for a "safe haven" for its survival and persistence according to different ecological niches, and strongly emphasize the need for careful H. pylori surveillance to improve management of the infection.

Indexed as

Anti-Bacterial AgentsBiofilmsHelicobacter InfectionsHelicobacter pyloriHumansStomachTreatment OutcomeAnti-Bacterial AgentsBiofilm in vitroBiofilm in vivoHelicobacter pyloriRoute of transmissionViable But Non Culturable state

Identifiers

PMID24914317
PMCPMC4024766
OpenAlexW2031804555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.