Evidence map›Paper›PMID 24913771›Full record

ArticleNeurosurgical review2015

An adult multifocal medulloblastoma with diffuse acute postoperative cerebellar swelling: immunohistochemical and molecular genetics analysis.

Vladimir Balik, Radek Trojanec, Milena Holzerova, Lucie Tuckova, Igor Sulla, Magdalena Megova, Miroslav Vaverka, Lumir Hrabalek, Jiri Ehrmann

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Neurosurgical review, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Multifocal medulloblastoma in an adult: a case report and review of the literature.Journal of cancer research and clinical oncology · 2025
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Vladimir BalikDepartment of Neurosurgery, University Hospital Olomouc and Faculty of Medicine and Dentistry, University Hospital Olomouc and Palacky University, Olomouc, Czech Republic, balik.vladimir@gmail.com.
Radek Trojanec
Milena Holzerova
Lucie Tuckova
Igor Sulla
Magdalena Megova
Miroslav Vaverka
Lumir Hrabalek
Jiri Ehrmann
Palacký University Olomouc · CZUniversity Hospital Olomouc · CZInstitute of Molecular and Translational Medicine · CZUniversity of Veterinary Medicine in Košice · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medulloblastoma (MB), the most common malignant tumor typically affecting children, occurs only exceptionally in adults. Multifocal presentation of this malignancy in adulthood is even much rarer—only four cases with favorable postoperative course have been reported, so far. The study illustrates a very rare rapid postoperative clinical deterioration due to diffuse cerebellar swelling (DCS) in an adult multifocal MB (MMB). To the best of their knowledge, authors for the first time performed genetic analysis of MMB and demonstrated expression patterns of selected markers that put the patient within the sonic hedgehog (SHH) molecular subgroup and at least partially explain her unsatisfactory clinical course. Herein, authors summarized the relevant literature concerning this issue with the aim to determine features that would facilitate diagnosis and therapy of such a scarce clinical entity.

Indexed as

ImmunohistochemistryPathology, MolecularAdultBrain EdemaCerebellar NeoplasmsFemaleHumansMedulloblastomaPostoperative Period

Identifiers

PMID24913771
OpenAlexW1977471670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.