Evidence map›Paper›PMID 24913223›Full record

ArticleOccupational and environmental medicine2014

Respiratory disease in United States farmers.

Jane A Hoppin, David M Umbach, Stuart Long, Jessica L Rinsky, Paul K Henneberger, Paivi M Salo, Darryl C Zeldin, Stephanie J London, Michael C R Alavanja, Aaron Blair and 2 more

Abstract read
In one paragraph

Article in Occupational and environmental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 79 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Early-life farm exposures and eczema among adults in the Agricultural Lung Health Study.The journal of allergy and clinical immunology. Global · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Indoor Airborne Microbial Concentration and Dry Eye.American journal of ophthalmology · 2021
    Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Jane A HoppinEpidemiology Branch, National Institute of Environmental Health Sciences, NIH/DHHS, Research Triangle Park, North Carolina, USA Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA.
David M UmbachBiostatistics Branch, National Institute of Environmental Health Sciences, NIH/DHHS, Research Triangle Park, North Carolina, USA.
Stuart LongWestat, Durham, North Carolina, USA.
Jessica L RinskyDepartment of Epidemiology, UNC Chapel Hill, Chapel Hill, North Carolina, USA.
Paul K HennebergerDivision of Respiratory Disease Studies, NIOSH, CDC, DHHS, Morgantown, West Virginia, USA.
Paivi M SaloLaboratory of Respiratory Biology, National Institute of Environmental Health Sciences, NIH/DHHS, Research Triangle Park, North Carolina, USA.
Darryl C ZeldinLaboratory of Respiratory Biology, National Institute of Environmental Health Sciences, NIH/DHHS, Research Triangle Park, North Carolina, USA.
Stephanie J LondonEpidemiology Branch, National Institute of Environmental Health Sciences, NIH/DHHS, Research Triangle Park, North Carolina, USA.
Michael C R AlavanjaOccupational and Environmental Epidemiology Branch, National Cancer Institute, NIH/DHHS, Rockville, Maryland, USA.
Aaron BlairOccupational and Environmental Epidemiology Branch, National Cancer Institute, NIH/DHHS, Rockville, Maryland, USA.
Laura E Beane FreemanOccupational and Environmental Epidemiology Branch, National Cancer Institute, NIH/DHHS, Rockville, Maryland, USA.
Dale P SandlerEpidemiology Branch, National Institute of Environmental Health Sciences, NIH/DHHS, Research Triangle Park, North Carolina, USA.
National Institute of Environmental Health Sciences · USUnited States Department of Health and Human Services · USUniversity of North Carolina at Chapel Hill · USWestat (United States) · US

Funding

Studies of Occupational Cancer (Pesticides)ZIACP010119 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI BEANE FREEMAN, LAURA · 2009 to 2025
$46.1M
Biostatstics for Research in Environmental HealthT32ES007018 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel, Rebecca Fry · 1985 to 2026
$31.3M
Health Effects Of Exposures In AgricultureZIAES049030 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 2009 to 2025
$11.2M
Indoor Allergens And AsthmaZIAES025041 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 2009 to 2025
$8.5M
Genetics and Environment in Adult Respiratory, Allergic and Cardiac diseaseZIAES043012 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE · 2009 to 2025
$6.4M
STUDIES OF OCCUPATIONAL CANCER--PESTICIDESZ01CP010119 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ALAVANJA, MICHAEL · 1996 to 2008
$5.0M
INDOOR ALLERGENS AND ASTHMAZ01ES025041 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 1998 to 2008
$1.9M
Environmental Exposures And Risk For Cancer and Chronic Diseases In AdultsZIAES049028 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 2009 to 2024
$1.6M
Statistical techniques applied to environmental health sciencesZIAES103126 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI UMBACH, DAVID M · 2012 to 2025
$1.0M
Intramural CDC HHS CC999999Intramural NIH HHS Z01 CP010119Intramural NIH HHS Z01 ES025041NCI NIH HHS Z01-CP010119NIEHS NIH HHS T32 ES007018NIEHS NIH HHS T32ES007018NIEHS NIH HHS Z01-ES025041
6 · The paper itself

Abstract

objectivesFarmers may be at increased risk for adverse respiratory outcomes compared with the general population due to their regular exposures to dusts, animals and chemicals. However, early life farm exposures to microbial agents may result in reduced risk. Understanding respiratory disease risk among farmers and identifying differences between farmers and other populations may lead to better understanding of the contribution of environmental exposures to respiratory disease risk in the general population.

methodsWe compared the prevalence of self-reported respiratory outcomes in 43548 participants from the Agricultural Health Study (AHS), a prospective cohort of farmers and their spouses from Iowa and North Carolina, with data from adult participants in the National Health and Nutrition Examination Survey (NHANES) over the same period (2005-2010).

resultsAHS participants had lower prevalences of respiratory diseases (asthma, adult-onset asthma, chronic bronchitis and emphysema), but higher prevalences of current respiratory symptoms (wheeze, cough and phlegm) even after controlling for smoking, body mass index and population characteristics. The overall prevalence of asthma in the AHS (7.2%, 95% CI 6.9 to 7.4) was 52% of that in NHANES (13.8%, 95% CI 13.3 to 14.3), although the prevalence of adult-onset asthma among men did not differ (3.6% for AHS, 3.7% for NHANES). Conversely, many respiratory symptoms were more common in the AHS than NHANES, particularly among men.

conclusionsThese findings suggest that farmers and their spouses have lower risk for adult-onset respiratory diseases compared with the general population, and potentially higher respiratory irritation as evidenced by increased respiratory symptoms.

Indexed as

AgricultureAdultAgedAged, 80 and overAir PollutantsAsthmaCoughFemaleHumansIowaMaleMiddle AgedMucusNorth CarolinaNutrition SurveysOccupational DiseasesAir Pollutants

Identifiers

PMID24913223
PMCPMC4542002
OpenAlexW1968434935

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.