Evidence map›Paper›PMID 24913164›Full record

ArticleAntimicrobial agents and chemotherapy2014

Emergence of VIM-2 and IMP-15 carbapenemases and inactivation of oprD gene in carbapenem-resistant Pseudomonas aeruginosa clinical isolates from Lebanon.

Charbel Al Bayssari, Seydina M Diene, Lotfi Loucif, Sushim Kumar Gupta, Fouad Dabboussi, Hassan Mallat, Monzer Hamze, Jean-Marc Rolain

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. The Emergence and Dissemination of Multidrug ResistantAntibiotics (Basel, Switzerland) · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Emergence of plasmid-encoded VIM-2-producingNew microbes and new infections · 2019
    Article
  12. Review
  13. Review
  14. Article
  15. Article
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Charbel Al BayssariAix-Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), UM63, CNRS 7278, IRD 198, Inserm 1095, IHU Méditerranée Infection, Faculté de Médecine et de Pharmacie, Marseille, France Université Libanaise, Ecole Doctorale de Sciences et de Technologie, Centre AZM pour la Recherche en Biotechnologie et ses Applications, Laboratoire de Microbiologie, Environnement et Santé, Tripoli, Lebanon.
Seydina M DieneAix-Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), UM63, CNRS 7278, IRD 198, Inserm 1095, IHU Méditerranée Infection, Faculté de Médecine et de Pharmacie, Marseille, France.
Lotfi LoucifAix-Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), UM63, CNRS 7278, IRD 198, Inserm 1095, IHU Méditerranée Infection, Faculté de Médecine et de Pharmacie, Marseille, France.
Sushim Kumar GuptaAix-Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), UM63, CNRS 7278, IRD 198, Inserm 1095, IHU Méditerranée Infection, Faculté de Médecine et de Pharmacie, Marseille, France.
Fouad DabboussiUniversité Libanaise, Ecole Doctorale de Sciences et de Technologie, Centre AZM pour la Recherche en Biotechnologie et ses Applications, Laboratoire de Microbiologie, Environnement et Santé, Tripoli, Lebanon.
Hassan MallatUniversité Libanaise, Ecole Doctorale de Sciences et de Technologie, Centre AZM pour la Recherche en Biotechnologie et ses Applications, Laboratoire de Microbiologie, Environnement et Santé, Tripoli, Lebanon.
Monzer HamzeUniversité Libanaise, Ecole Doctorale de Sciences et de Technologie, Centre AZM pour la Recherche en Biotechnologie et ses Applications, Laboratoire de Microbiologie, Environnement et Santé, Tripoli, Lebanon.
Jean-Marc RolainAix-Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), UM63, CNRS 7278, IRD 198, Inserm 1095, IHU Méditerranée Infection, Faculté de Médecine et de Pharmacie, Marseille, France jean-marc.rolain@univ-amu.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report here the emergence of VIM-2 and IMP-15 carbapenemases in a series of clinical isolates of carbapenem-resistant Pseudomonas aeruginosa in Lebanon. We also describe the disruption of the oprD gene by either mutations or insertion sequence (IS) elements ISPa1328 and ISPre2 isoform. Our study reemphasizes a rapid dissemination of the VIM-2 carbapenemase-encoding gene in clinical isolates of P. aeruginosa in the Mediterranean basin.

Indexed as

Anti-Bacterial AgentsBacterial Typing Techniquesbeta-Lactamasesbeta-Lactam ResistanceCarbapenemsDNA, IntergenicHospitalsHumansLebanonMutationPhylogenyPorinsPseudomonas aeruginosaPseudomonas InfectionsAnti-Bacterial Agentsbeta-lactamase bla(vim-2)beta-lactamase IMP-15, Pseudomonas aeruginosabeta-LactamasesCarbapenemsDNA, IntergenicOprD protein, Pseudomonas aeruginosaPorins

Identifiers

PMID24913164
PMCPMC4136035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.