Evidence map›Paper›PMID 24911812›Full record

ArticleAnnals of vascular surgery2014

Improving outcomes for diabetic patients undergoing revascularization for critical limb ischemia: does the quality of outpatient diabetic care matter?

Benjamin S Brooke, Larry W Kraiss, David H Stone, Brian Nolan, Randall R De Martino, Gayle E Reiber, David C Goodman, Jack L Cronenwett, Philip P Goodney

Abstract read
In one paragraph

Article in Annals of vascular surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Epidemiology and Outcome of Nontraumatic Lower Limb Amputations.Medical journal of the Islamic Republic of Iran · 2023
    Article
  4. Review
  5. Article
  6. Article
  7. High hemoglobin AJournal of vascular surgery · 2018
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Benjamin S BrookeDivision of Vascular Surgery, University of Utah School of Medicine, Salt Lake City, UT. Electronic address: Benjamin.Brooke@hsc.utah.edu.
Larry W KraissDivision of Vascular Surgery, University of Utah School of Medicine, Salt Lake City, UT.
David H StoneSection of Vascular Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Brian NolanSection of Vascular Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH; Dartmouth Institute for Health Policy & Clinical Practice, Lebanon, NH.
Randall R De MartinoDivision of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, MN.
Gayle E ReiberDepartment of Health Services & Epidemiology, University of Washington, Seattle, WA.
David C GoodmanDartmouth Institute for Health Policy & Clinical Practice, Lebanon, NH.
Jack L CronenwettSection of Vascular Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Philip P GoodneySection of Vascular Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH; Dartmouth Institute for Health Policy & Clinical Practice, Lebanon, NH.

Funding

Understanding Variation in Treatment Intensity with Lower Extremity PADK08HL105676 · NHLBI · DARTMOUTH COLLEGE · PI GOODNEY, PHILIP P · 2010 to 2014
$700k
NHLBI NIH HHS K08 HL105676
6 · The paper itself

Abstract

backgroundDiabetic patients who undergo lower extremity surgical revascularization for critical limb ischemia (CLI) are at high risk for amputation or death, even when their inpatient procedures are successful. We hypothesized that postoperative outcomes might be improved in regions where diabetics with CLI receive more frequent high-quality outpatient care.

methodsA retrospective cohort study was performed among 172,134 patients with CLI (52% male, 15% black, mean age 76 years) who underwent open and endovascular lower extremity revascularization procedures using Medicare claims (2004-2007), which included 84,653 (49%) beneficiaries who were diabetic. Regional utilization of annual serum cholesterol and hemoglobin A1c testing were used to assess the quality of outpatient diabetic care. We examined relationships between frequency of diabetic testing with amputation-free survival (AFS), major adverse limb events (MALE), and rates of readmission across all US hospital referral regions.

resultsThere was significant regional variation in annual serum cholesterol and hemoglobin A1c testing across the United States (87% highest quartile vs. 59% lowest quartile, P < 0.01). Compared with the lowest quartile of diabetic testing, diabetic patients undergoing lower extremity revascularization in regions with the highest quartile of diabetic testing had significantly improved AFS (hazards ratio [HR]: 0.94, 95% confidence interval [CI]: 0.90-0.97; P < 0.01) and MALE (HR: 0.92, 95% CI: 0.89-0.96; P < 0.01) persisting up to 2 years after lower extremity revascularization, even after adjusting for procedure type, gender, age, race, and comorbidities. Moreover, the risk of 30-day readmission was significantly reduced in regions with the highest versus lowest quartile of diabetic testing (odds ratio: 0.91, 95% CI: 0.85-0.97; P < 0.01). Nondiabetic patients with CLI, in comparison, did not benefit to the same extent from undergoing revascularization in regions with high-quality outpatient diabetic care.

conclusionsDiabetic patients undergoing lower extremity revascularization in regions with higher utilization of diabetic care quality measures have significantly better long-term limb salvage and readmission outcomes. Our study underscores the importance of providing optimal outpatient care to diabetics following vascular surgery and outlines a potential strategy for quality improvement in these high-risk patients.

Indexed as

Endovascular ProceduresQuality Indicators, Health CareAgedAged, 80 and overBiomarkersCholesterolComorbidityDiabetic AngiopathiesFemaleGlycated HemoglobinHumansIschemiaLimb SalvageLower ExtremityMalePatient ReadmissionBiomarkersCholesterolGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID24911812
PMCPMC4165745

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.