ArticleThe Science of the total environment2014
Organochlorine pesticide levels in maternal serum and risk of neural tube defects in offspring in Shanxi Province, China: a case-control study.
Article in The Science of the total environment, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- A Comprehensive Review of Data-Driven Techniques for Air Pollution Concentration Forecasting.Sensors (Basel, Switzerland) · 2025Review
- Review
- Association of pesticide exposure with human congenital abnormalities.Toxicology and applied pharmacology · 2018Review
- Levels of folate receptor autoantibodies in maternal and cord blood and risk of neural tube defects in a Chinese population.Birth defects research. Part A, Clinical and molecular teratology · 2016Article
- Levels of polycyclic aromatic hydrocarbons in maternal serum and risk of neural tube defects in offspring.Environmental science & technology · 2015Article
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Authors and funding
10 authors.
Funding
Abstract
Organochlorine pesticides (OCPs) in placental tissue have been reported to be associated with an increased risk for fetal neural tube defects (NTDs). Our case-control study was performed to explore the association between maternal serum OCP concentration and NTD risk in offspring. Serum samples were collected from 117 mothers who delivered NTD infants (case group) and 121 mothers who delivered healthy infants (control group). Only three of the 25 OCPs were detected in more than half of the maternal serum samples. The median concentration of total OCPs in the case group was significantly higher than that of the control group. However, no dose-response relationships between higher levels of any individual OCPs or total OCPs and the risk of NTDs or subtypes were observed in either the unadjusted binary unconditional logistic regression model or the model adjusted by potential confounders. We conclude that no clear association between maternal serum OCP residues and NTD risk in offspring was observed in this population. CAPSULE: No clear association between maternal serum levels of organochlorine pesticides and risk of neural tube defects in offspring was observed for a Chinese population.
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