Evidence map›Paper›PMID 24911500›Full record

ArticleNature biotechnology2014

The Synthetic Biology Open Language (SBOL) provides a community standard for communicating designs in synthetic biology.

Michal Galdzicki, Kevin P Clancy, Ernst Oberortner, Matthew Pocock, Jacqueline Y Quinn, Cesar A Rodriguez, Nicholas Roehner, Mandy L Wilson, Laura Adam, J Christopher Anderson and 22 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature biotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Specifications of Standards in Systems and Synthetic Biology.Journal of integrative bioinformatics · 2015
    Guideline
  2. Article
  3. Review
  4. Review
  5. Article
  6. SynVectorDB: embedding-based retrieval system for synthetic biology parts.Database : the journal of biological databases and curation · 2026
    Article
  7. Article
  8. Article
  9. Design biology and mind-body health.Journal, genetic engineering & biotechnology · 2025
    Review
  10. Article
  11. Review
  12. BioPAX in 2024: Where we are and where we are heading.Computational and structural biotechnology journal · 2024
    Review
  13. Review
  14. Article
  15. Energy Aware Technology Mapping of Genetic Logic Circuits.bioRxiv : the preprint server for biology · 2024
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

32 authors.

Michal GaldzickiBiomedical and Health Informatics, University of Washington, Seattle, Washington, USA.ORCID 0000000283928183
Kevin P ClancySynthetic Biology Unit, Life Technologies, Carlsbad, California, USA.
Ernst OberortnerDepartment of Electrical and Computer Engineering, Boston University, Boston, Massachusetts, USA.
Matthew PocockSchool of Computing Science, Newcastle University, Newcastle upon Tyne, UK.
Jacqueline Y QuinnAutodesk Research, Autodesk, San Francisco, California, USA.
Cesar A RodriguezAutodesk Research, Autodesk, San Francisco, California, USA.
Nicholas RoehnerBioengineering, University of Utah, Salt Lake City, Utah, USA.
Mandy L WilsonVirginia Bioinformatics Institute, Virginia Tech, Blacksburg, Virginia, USA.ORCID 0000000247785744
Laura AdamVirginia Bioinformatics Institute, Virginia Tech, Blacksburg, Virginia, USA.
J Christopher AndersonDepartment of Bioengineering, University of California, Berkeley, Berkeley, California, USA.
Bryan A BartleyDepartment of Bioengineering, University of Washington, Seattle, Washington, USA.
Jacob BealRaytheon BBN Technologies, Cambridge, Massachusetts, USA.
Deepak ChandranAutodesk Research, Autodesk, San Francisco, California, USA.
Joanna ChenFuels Synthesis Division, Joint Bioenergy Institute (JBEI), Berkeley, California, USA.
Douglas DensmoreDepartment of Electrical and Computer Engineering, Boston University, Boston, Massachusetts, USA.
Drew EndyDepartment of Bioengineering, Stanford University, Stanford, California, USA.
Raik GrünbergIRIC, University of Montreal, Montreal, Quebec, Canada.
Jennifer HallinanSchool of Computing Science, Newcastle University, Newcastle upon Tyne, UK.
Nathan J HillsonFuels Synthesis Division, Joint Bioenergy Institute (JBEI), Berkeley, California, USA.
Jeffrey D JohnsonPlant and Microbial Biology, University of California, Berkeley, Berkeley, California, USA.
Allan KuchinskyMolecular Tools Laboratory, Agilent Technologies, Santa Clara, California, USA.
Matthew LuxVirginia Bioinformatics Institute, Virginia Tech, Blacksburg, Virginia, USA.
Goksel MisirliSchool of Computing Science, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000000224547188
Jean PeccoudVirginia Bioinformatics Institute, Virginia Tech, Blacksburg, Virginia, USA.ORCID 0000000176496127
Hector A PlaharFuels Synthesis Division, Joint Bioenergy Institute (JBEI), Berkeley, California, USA.
Evren SirinClark & Parsia, Arlington, Massachusetts, USA.
Guy-Bart StanBioengineering, Imperial College London, London, UK.
Alan VillalobosDNA2.0, Menlo Park, California, USA.
Anil WipatSchool of Computing Science, Newcastle University, Newcastle upon Tyne, UK.
John H GennariBiomedical and Health Informatics, University of Washington, Seattle, Washington, USA.
Chris J MyersDepartment of Electrical and Computer Engineering, University of Utah, Salt Lake City, Utah, USA.
Herbert M SauroDepartment of Bioengineering, University of Washington, Seattle, Washington, USA.ORCID 0000000236596817

Funding

University of Washington Biomedical Informatics and Data Science Research Training ProgramT15LM007442 · NLM · UNIVERSITY OF WASHINGTON · PI JOHN H. GENNARI, Andrea L. Hartzler · 2002 to 2026
$19.6M
A synthetic biology library for the Semantic WebR42HG006737 · NHGRI · CLARK AND PARSIA, LLC · PI GENNARI, JOHN H., SIRIN, EVREN · 2011 to 2012
$848k
A synthetic biology library for the Semantic WebR41LM010745 · NLM · CLARK AND PARSIA, LLC · PI GENNARI, JOHN H., SIRIN, EVREN · 2010 to 2010
$100k
NHGRI NIH HHS R42 HG006737NLM NIH HHS R41 LM010745NLM NIH HHS T15 LM007442
6 · The paper itself

Abstract

The re-use of previously validated designs is critical to the evolution of synthetic biology from a research discipline to an engineering practice. Here we describe the Synthetic Biology Open Language (SBOL), a proposed data standard for exchanging designs within the synthetic biology community. SBOL represents synthetic biology designs in a community-driven, formalized format for exchange between software tools, research groups and commercial service providers. The SBOL Developers Group has implemented SBOL as an XML/RDF serialization and provides software libraries and specification documentation to help developers implement SBOL in their own software. We describe early successes, including a demonstration of the utility of SBOL for information exchange between several different software tools and repositories from both academic and industrial partners. As a community-driven standard, SBOL will be updated as synthetic biology evolves to provide specific capabilities for different aspects of the synthetic biology workflow.

Indexed as

Terminology as TopicVocabulary, ControlledInformation DisseminationInternationalityReference StandardsResearch DesignSoftwareSynthetic Biology

Identifiers

PMID24911500

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.