ArticleJournal of ethnopharmacology2014
Some Nigerian anti-tuberculosis ethnomedicines: a preliminary efficacy assessment.
Article in Journal of ethnopharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Medicinal Plants in the Treatment of Tuberculosis: A Systematic Review.Central nervous system agents in medicinal chemistry · 2025Pooled it
- Traditional Medicinal Plants as a Source of Antituberculosis Drugs: A System Review.BioMed research international · 2021Pooled it
- Increasing detection of individuals with tuberculosis through engagement of informal health care providers in Northeastern Nigeria.BMC public health · 2026Article
- Traditional use of Garcinia kola Heckel in Nigeria - the results of questionnaire survey compared with scientific evidence.BMC complementary medicine and therapies · 2026Article
- Traditional medicinal plants used in the treatment of tuberculosis in Ethiopia: A systematic review.Heliyon · 2022Review
- HPLC-DAD and UHPLC/QTOF-MS Analysis of Polyphenols in Extracts of the African SpeciesAntibiotics (Basel, Switzerland) · 2020Article
- Ethnobotanical Survey of Plants Used for Treating Cough Associated with Respiratory Conditions in Ede South Local Government Area of Osun State, Nigeria.Plants (Basel, Switzerland) · 2020Article
- Article
- Antimicrobial activity of Nigerian medicinal plants.Journal of intercultural ethnopharmacologyReview
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13 authors.
Funding
Abstract
ethnopharmacological significanceNigerian herbalists possess indigenous ethnomedicinal recipes for the management of tuberculosis and related ailments. A collaborative preliminary modern scientific evaluation of the efficacy of some Nigerian ethnomedicines used by traditional medicine practitioners (TMPs) in the management of tuberculosis and related ailments has been carried out. MATERIALS AND
methodsEthnomedicinal recipes (ETMs) were collected from TMPs from locations in various ecological zones of Nigeria under a collaborative understanding. The aqueous methanolic extracts of the ETMs were screened against Mycobacterium bovis, BCG and Mycobacterium tuberculosis strain H37Rv using the broth microdilution method.
resultsExtracts of ETMs screened against BCG showed 69% activity against the organism. The activities varied from weak, ≤2500 µg/mL to highly active, 33 µg/mL 64% of the extracts were active against Mycobacterium tuberculosis The activities of the extracts against Mycobacterium tuberculosis varied from weak, ≤2500 µg/mL to highly active, 128 µg/mL. There was 77% agreement in results obtained using BCG or Mycobacterium tuberculosis as test organisms.
conclusionThe results show clear evidence for the efficacy of the majority of indigenous Nigerian herbal recipes in the ethnomedicinal management of tuberculosis and related ailments. BCG may be effectively used, to a great extent, as the organism for screening for potential anti-Mycobacterium tuberculosis agents. A set of prioritization criteria for the selection of plants for initial further studies for the purpose of antituberculosis drug discovery research is proposed.
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