ReviewHearing research2014
The auditory corticocollicular system: molecular and circuit-level considerations.
Review in Hearing research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed.
- Article
- Cell type-specific plasticity in synaptic, intrinsic, and sound response properties of deep-layer cortical neurons after noise trauma.Science advances · 2025Article
- Microglial Engulfment of Multisensory Terminals in the Midbrain Inferior Colliculus During an Early Critical Period.The Journal of comparative neurology · 2025Article
- Article
- A sensory-motor theory of the neocortex.Nature neuroscience · 2024Review
- Recurrent Circuits Amplify Corticofugal Signals and Drive Feedforward Inhibition in the Inferior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Increased pyramidal and VIP neuronal excitability in rat primary auditory cortex directly correlates with tinnitus behaviour.The Journal of physiology · 2023Article
- Differential projections from the cochlear nucleus to the inferior colliculus in the mouse.Frontiers in neural circuits · 2023Article
- Descending projections to the auditory midbrain: evolutionary considerations.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2023Review
- The nuclei of the lateral lemniscus: unexpected players in the descending auditory pathway.Frontiers in neuroanatomy · 2023Article
- Distinct topographic organization and network activity patterns of corticocollicular neurons within layer 5 auditory cortex.Frontiers in neural circuits · 2023Article
- Diverse functions of the auditory cortico-collicular pathway.Hearing research · 2022Review
- Altered processing of communication signals in the subcortical auditory sensory pathway in autism.Human brain mapping · 2022Article
- Corticofugal regulation of predictive coding.eLife · 2022Article
- Article
- Bilateral Interactions in the Mouse Dorsal Inferior Colliculus Enhance the Ipsilateral Neuronal Responses and Binaural Hearing.Frontiers in physiology · 2022Article
- Segregation of Multimodal Inputs Into Discrete Midbrain Compartments During an Early Critical Period.Frontiers in neural circuits · 2022Article
- Patterns of Unilateral and Bilateral Projections From Layers 5 and 6 of the Auditory Cortex to the Inferior Colliculus in Mouse.Frontiers in systems neuroscience · 2021Article
- Behavioral Approaches to Study Top-Down Influences on Active Listening.Frontiers in neuroscience · 2021Article
- Circuit Mechanisms Underlying the Segregation and Integration of Parallel Processing Streams in the Inferior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
We live in a world imbued with a rich mixture of complex sounds. Successful acoustic communication requires the ability to extract meaning from those sounds, even when degraded. One strategy used by the auditory system is to harness high-level contextual cues to modulate the perception of incoming sounds. An ideal substrate for this process is the massive set of top-down projections emanating from virtually every level of the auditory system. In this review, we provide a molecular and circuit-level description of one of the largest of these pathways: the auditory corticocollicular pathway. While its functional role remains to be fully elucidated, activation of this projection system can rapidly and profoundly change the tuning of neurons in the inferior colliculus. Several specific issues are reviewed. First, we describe the complex heterogeneous anatomical organization of the corticocollicular pathway, with particular emphasis on the topography of the pathway. We also review the laminar origin of the corticocollicular projection and discuss known physiological and morphological differences between subsets of corticocollicular cells. Finally, we discuss recent findings about the molecular micro-organization of the inferior colliculus and how it interfaces with corticocollicular termination patterns. Given the assortment of molecular tools now available to the investigator, it is hoped that his review will help guide future research on the role of this pathway in normal hearing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.