ArticleEnvironmental health perspectives2014
Particulate matter air pollution exposure, distance to road, and incident lung cancer in the nurses' health study cohort.
Article in Environmental health perspectives, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 7 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
67 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Impact of Pollution on Cancer: A Systematic Review and Meta-Analysis with Focus on Air Pollution.International journal of environmental research and public health · 2026Pooled it
- Assessing the Global Impact of Ambient Air Pollution on Cancer Incidence and Mortality: A Comprehensive Meta-Analysis.JCO global oncology · 2024Pooled it
- Impacts of Outdoor Particulate Matter Exposure on the Incidence of Lung Cancer and Mortality.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Characteristics of cohort studies of long-term exposure to PMEnvironmental science and pollution research international · 2019Pooled it
- Relationship between exposure to PM2.5 and lung cancer incidence and mortality: A meta-analysis.Oncotarget · 2017Pooled it
- Lung Cancer and Exposure to Nitrogen Dioxide and Traffic: A Systematic Review and Meta-Analysis.Environmental health perspectives · 2015Pooled it
- Outdoor particulate matter exposure and lung cancer: a systematic review and meta-analysis.Environmental health perspectives · 2014Pooled it
- Hallmarks of lung cancer driven by inhalable particulate matter: From cell-intrinsic oncogenic traits to microenvironment remodeling.Innovation (Cambridge (Mass.)) · 2026Review
- Air pollution and the risk of second primary lung cancer among lung cancer survivors: the prospective UK Biobank cohort study.British journal of cancer · 2026Article
- Trends, inequalities, and 2030 projections of women's tracheal, bronchial, and lung cancer attributable to air pollution, radon, and tobacco exposure.Frontiers in global women's health · 2026Article
- Ambient air pollution exposure and lung cancer risk in a large prospective U.S. cohort.The Science of the total environment · 2025Article
- Long-term exposure to air pollution and lung cancer incidence: findings from improved exposure assessment and extended population.Cancer causes & control : CCC · 2025Article
- Lung cancer clusters and air pollution exposure in Wayne County, Michigan: an autoregressive distributed lag model.Journal of thoracic disease · 2025Article
- Effect of Long-Term Fine Particulate Matter Exposure on Lung Cancer Incidence and Mortality in Chinese Nonsmokers.American journal of respiratory and critical care medicine · 2025Article
- Long-term exposure to fine particulate matter, ozone, and greenness and the risk of lung cancer: a retrospective cohort analysis within a national sample cohort.Frontiers in public health · 2025Article
- Air quality and cancer risk in the All of Us Research Program.Cancer causes & control : CCC · 2024Article
- Outdoor Ultrafine Particulate Matter and Risk of Lung Cancer in Southern California.American journal of respiratory and critical care medicine · 2024Article
- Interpretable Machine Learning Approaches for Forecasting and Predicting Air Pollution: A Systematic Review.Aerosol and air quality research · 2024Article
- Long-term association of air pollution and incidence of lung cancer among older Americans: A national study in the Medicare cohort.Environment international · 2023Article
- Exposure to low-level ambient air pollution and the relationship with lung and bladder cancer in older men, in Perth, Western Australia.British journal of cancer · 2023Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundA body of literature has suggested an elevated risk of lung cancer associated with particulate matter and traffic-related pollutants.
objectiveWe examined the relation of lung cancer incidence with long-term residential exposures to ambient particulate matter and residential distance to roadway, as a proxy for traffic-related exposures.
methodsFor participants in the Nurses' Health Study, a nationwide prospective cohort of women, we estimated 72-month average exposures to PM2.5, PM2.5-10, and PM10 and residential distance to road. Follow-up for incident cases of lung cancer occurred from 1994 through 2010. Cox proportional hazards models were adjusted for potential confounders. Effect modification by smoking status was examined.
resultsDuring 1,510,027 person-years, 2,155 incident cases of lung cancer were observed among 103,650 participants. In fully adjusted models, a 10-μg/m3 increase in 72-month average PM10 [hazard ratio (HR) = 1.04; 95% CI: 0.95, 1.14], PM2.5 (HR = 1.06; 95% CI: 0.91, 1.25), or PM2.5-10 (HR = 1.05; 95% CI: 0.92, 1.20) was positively associated with lung cancer. When the cohort was restricted to never-smokers and to former smokers who had quit at least 10 years before, the associations appeared to increase and were strongest for PM2.5 (PM10: HR = 1.15; 95% CI: 1.00, 1.32; PM2.5: HR = 1.37; 95% CI: 1.06, 1.77; PM2.5-10: HR = 1.11; 95% CI: 0.90, 1.37). RESULTS were most elevated when restricted to the most prevalent subtype, adenocarcinomas. Risks with roadway proximity were less consistent.
conclusionsOur findings support those from other studies indicating increased risk of incident lung cancer associated with ambient PM exposures, especially among never- and long-term former smokers.
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