ReviewAnnual review of chemical and biomolecular engineering2014
A new toolbox for assessing single cells.
Review in Annual review of chemical and biomolecular engineering, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Recent advance in dual-functional luminescent probes for reactive species and common biological ions.Analytical and bioanalytical chemistry · 2022Review
- The Metabolic Flux Probe (MFP)-Secreted Protein as a Non-Disruptive Information Carrier forInternational journal of molecular sciences · 2021Article
- Article
- Novel computational model of gastrula morphogenesis to identify spatial discriminator genes by self-organizing map (SOM) clustering.Scientific reports · 2019Article
- Dynamic secretome of bone marrow-derived stromal cells reveals a cardioprotective biochemical cocktail.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- From isolated structures to continuous networks: A categorization of cytoskeleton-based motile engineered biological microstructures.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2019Review
- Replicating and Cycling Stores of Information Perpetuate Life.BioEssays : news and reviews in molecular, cellular and developmental biology · 2018Article
- In situ exploration of characteristics of macropinocytosis and size range of internalized substances in cells by 3D-structured illumination microscopy.International journal of nanomedicine · 2018Article
- Aerobiology: Experimental Considerations, Observations, and Future Tools.Applied and environmental microbiology · 2017Review
- Single cell biology beyond the era of antibodies: relevance, challenges, and promises in biomedical research.Cellular and molecular life sciences : CMLS · 2017Review
- Development of Droplet Microfluidics Enabling High-Throughput Single-Cell Analysis.Molecules (Basel, Switzerland) · 2016Review
- Microfluidic Sample Preparation for Single Cell Analysis.Analytical chemistry · 2016Review
- Single-Cell Analysis in Cancer Genomics.Trends in genetics : TIG · 2015Review
- Optimization of the cytokine secretion assay for human IL-2 in single and combination assays.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2015Article
- Inferring cell differentiation processes based on phylogenetic analysis of genome-wide epigenetic information: hematopoiesis as a model case.Genome biology and evolution · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Unprecedented access to the biology of single cells is now feasible, enabled by recent technological advancements that allow us to manipulate and measure sparse samples and achieve a new level of resolution in space and time. This review focuses on advances in tools to study single cells for specific areas of biology. We examine both mature and nascent techniques to study single cells at the genomics, transcriptomics, and proteomics level. In addition, we provide an overview of tools that are well suited for following biological responses to defined perturbations with single-cell resolution. Techniques to analyze and manipulate single cells through soluble and chemical ligands, the microenvironment, and cell-cell interactions are provided. For each of these topics, we highlight the biological motivation, applications, methods, recent advances, and opportunities for improvement. The toolbox presented in this review can function as a starting point for the design of single-cell experiments.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.