ArticleGut pathogens2014
Analysis of the role of the Cronobacter sakazakii ProP homologues in osmotolerance.
Article in Gut pathogens, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- How Salmonella Works Under Osmotic and Desiccation Stresses.Comprehensive reviews in food science and food safety · 2026Review
- Microbiological Characterization of Baru Nuts From the Cerrado Biome, Brazil.Journal of food science · 2026Article
- Foodborne pathogens in Africa: UnderstandingPublic health challenges · 2023Review
- Microbiological Quality of Nuts, Dried and Candied Fruits, Including the Prevalence ofPathogens (Basel, Switzerland) · 2021Article
- The genome of Ensifer alkalisoli YIC4027 provides insights for host specificity and environmental adaptations.BMC genomics · 2019Article
- Daqu Fermentation Selects for Heat-Resistant Enterobacteriaceae and Bacilli.Applied and environmental microbiology · 2018Article
- Caco-2 Invasion byFrontiers in microbiology · 2017Article
- The Effect of Pyrroloquinoline Quinone on the Expression of WISP1 in Traumatic Brain Injury.Stem cells international · 2017Article
- Under the microscope: From pathogens to probiotics and back.Bioengineered · 2015Review
- Functional Screening of the Cronobacter sakazakii BAA-894 Genome reveals a role for ProP (ESA_02131) in carnitine uptake.Bioengineered · 2015Article
- The role of the Cronobacter sakazakii ProP C-terminal coiled coil domain in osmotolerance.Gut pathogens · 2014Article
- Cronobacter sakazakii: stress survival and virulence potential in an opportunistic foodborne pathogen.Gut microbes · 2014Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteria respond to elevated osmolality by the accumulation of a range of low molecular weight molecules, known as compatible solutes (owing to their compatibility with the cells' normal physiology at high internal concentrations). The neonatal pathogen Cronobacter sakazakii is uniquely osmotolerant, surviving in powdered infant formula (PIF) which typically has a water activity (aw) of 0.2 - inhospitable to most micro-organisms. Mortality rates of up to 80% in infected infants have been recorded making C. sakazakii a serious cause for concern. In silico analysis of the C. sakazakii BAA-894 genome revealed seven copies of the osmolyte uptake system ProP. Herein, we test the physiological role of each of these homologues following heterologous expression against an osmosensitive Escherichia coli host.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.