ArticleDose-response : a publication of International Hormesis Society2014
Low dose radiation adaptive protection to control neurodegenerative diseases.
Article in Dose-response : a publication of International Hormesis Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The trial behind it
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Who cites it
21 citing papers in PubMed, 29 citations in OpenAlex.
- Central and peripheral analgesia in irradiated rats: reserpine-induced pain model.Scientific reports · 2026Article
- Dose-Dependent Dual Effects of Gradient Ionizing Radiation on Neurocognition.International journal of molecular sciences · 2026Review
- Gamma radiation improves AD pathogenesis in APP/PS1 mouse model by potentiating insulin sensitivity.Heliyon · 2020Article
- Low dose radiation prevents doxorubicin-induced cardiotoxicity.Oncotarget · 2018Article
- Acceleration of skin wound healing by low-dose indirect ionizing radiation in male rats.The Kaohsiung journal of medical sciences · 2017Article
- Anti-apoptotic and antioxidant effects of low dose gamma irradiation against diabetes-induced brain injury in rats.Radiation and environmental biophysics · 2016Article
- The impact of high and low dose ionising radiation on the central nervous system.Redox biology · 2016Review
- Ion mobility-enhanced MS(E)-based label-free analysis reveals effects of low-dose radiation post contextual fear conditioning training on the mouse hippocampal proteome.Journal of proteomics · 2016Article
- Low-dose ionizing radiation induces mitochondrial fusion and increases expression of mitochondrial complexes I and III in hippocampal neurons.Oncotarget · 2015Article
- Point/Counterpoint: low-dose radiation is beneficial, not harmful.Medical physics · 2014Article
- Correcting systemic deficiencies in our scientific infrastructure.Dose-response : a publication of International Hormesis Society · 2014Article
- Addition of diagnostic CT scan does not increase the cancer risk in patients undergoing SPECT studies: comment on Brix et al.: radiation risk and protection of patients in clinical SPECT/CT.European journal of nuclear medicine and molecular imaging · 2014Article
- Health Impacts of Low-Dose Ionizing Radiation: Current Scientific Debates and Regulatory Issues.Dose-response : a publication of International Hormesis SocietyReview
- Application of Low Doses of Ionizing Radiation in Medical Therapies.Dose-response : a publication of International Hormesis SocietyArticle
- Response to Commentary: Treating Alzheimer Dementia With CT-Induced Low-Dose Ionizing Radiation: Problematic, Yet Potential for More Precise Inquiry.Dose-response : a publication of International Hormesis SocietyArticle
- Treatment of Alzheimer Disease With CT Scans: A Case Report.Dose-response : a publication of International Hormesis SocietyArticle
- Low-Dose Ionizing Radiation Therapy: A Novel Treatment for Post-Concussion Syndrome?Dose-response : a publication of International Hormesis SocietyArticle
- Treatment of Early-Stage Alzheimer's Disease With CT Scans of the Brain: A Case Report.Dose-response : a publication of International Hormesis SocietyArticle
- Apigenin and Exposure to Low Dose Gamma Radiation Ameliorate Acetic Acid-Induced Ulcerative Colitis in Rats.Dose-response : a publication of International Hormesis SocietyArticle
- Treatment of Cancer and Inflammation With Low-Dose Ionizing Radiation: Three Case Reports.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Concerns have been expressed recently regarding the observed increased DNA damage from activities such as thinking and exercise. Such concerns have arisen from an incomplete accounting of the full effects of the increased oxidative damage. When the effects of the induced adaptive protective responses such as increased antioxidants and DNA repair enzymes are taken into consideration, there would be less endogenous DNA damage during the subsequent period of enhanced defenses, resulting in improved health from the thinking and exercise activities. Low dose radiation (LDR), which causes oxidative stress and increased DNA damage, upregulates adaptive protection systems that may decrease diseases in an analogous manner. Though there are ongoing debates regarding LDR's carcinogenicity, with two recent advisory committee reports coming to opposite conclusions, data published since the time of the reports have overwhelmingly ruled out its carcinogenicity, paving the way for consideration of its potential use for disease reduction. LDR adaptive protection is a promising approach to control neurodegenerative diseases, for which there are no methods of prevention or cure. Preparation of a compelling ethics case would pave the way for LDR clinical studies and progress in dealing with neurodegenerative diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.