ArticleScientific reports2014
Electrochemical detection of intracellular and cell membrane redox systems in Saccharomyces cerevisiae.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
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- Modification ofMolecules (Basel, Switzerland) · 2025Article
- Triple-Barrel Ultramicroelectrodes for Multipurpose, Submilliliter Electroanalysis.Analytical chemistry · 2023Article
- Review
- Direct Electricity Production fromInternational journal of molecular sciences · 2022Article
- Engineering bacteria to control electron transport altering the synthesis of non-native polymer.RSC advances · 2021Article
- Electrochromogenic Detection of Live Bacteria Using Soluble and Insoluble Prussian Blue.ACS omega · 2021Article
- From Microorganism-Based Amperometric Biosensors towards Microbial Fuel Cells.Sensors (Basel, Switzerland) · 2021Review
- Microbial Electrochemical Systems: Principles, Construction and Biosensing Applications.Sensors (Basel, Switzerland) · 2021Review
- Bioelectrical understanding and engineering of cell biology.Journal of the Royal Society, Interface · 2020Article
- Designing and optimization of an electrochemical substitute for the MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) cell viability assay.Scientific reports · 2019Article
- Electrochemical Response ofBiosensors · 2019Article
- Interrogating metabolism as an electron flow system.Current opinion in systems biology · 2019Review
- Synthesis of Polypyrrole Induced by [Fe(CN)₆]Polymers · 2018Article
- New Perspectives on Iron Uptake in Eukaryotes.Frontiers in molecular biosciences · 2018Review
- Novel T-C@AgNPs mediated biocidal mechanism against biofilm associated methicillin-resistantMedChemComm · 2017Article
- Electronic control of gene expression and cell behaviour in Escherichia coli through redox signalling.Nature communications · 2017Article
- Different characteristics between menadione and menadione sodium bisulfite as redox mediator in yeast cell suspension.Biochemistry and biophysics reports · 2016Article
- Electronic communication of cells with a surface mediated by boronic acid saccharide interactions.Chemical communications (Cambridge, England) · 2015Article
- Neural Cell Chip Based Electrochemical Detection of Nanotoxicity.Nanomaterials (Basel, Switzerland) · 2015Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Redox mediators can interact with eukaryote cells at a number of different cell locations. While cell membrane redox centres are easily accessible, the redox centres of catabolism are situated within the cytoplasm and mitochondria and can be difficult to access. We have systematically investigated the interaction of thirteen commonly used lipophilic and hydrophilic mediators with the yeast Saccharomyces cerevisiae. A double mediator system is used in which ferricyanide is the final electron acceptor (the reporter mediator). After incubation of cells with mediators, steady state voltammetry of the ferri/ferrocyanide redox couple allows quantitation of the amount of mediator reduced by the cells. The plateau current at 425 mV vs Ag/AgCl gives the analytical signal. The results show that five of the mediators interact with at least three different trans Plasma Membrane Electron Transport systems (tPMETs), and that four mediators cross the plasma membrane to interact with cytoplasmic and mitochondrial redox molecules. Four of the mediators inhibit electron transfer from S. cerevisiae. Catabolic inhibitors were used to locate the cellular source of electrons for three of the mediators.
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