ArticleDevelopment and psychopathology2014
The contributions of early adverse experiences and trajectories of respiratory sinus arrhythmia on the development of neurobehavioral disinhibition among children with prenatal substance exposure.
Article in Development and psychopathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Prenatal substance exposure and early childhood adversity: implications for child autonomic functioning at early school-age.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Article
- Change in maternal harshness and home environment across early childhood as predictors of autonomic regulation in adolescence in the context of prenatal substance exposure.Child development · 2026Article
- Mother-Infant Physiological Coregulation Is Associated With Infant Developmental Status Among Families With Experienced Adversity.Developmental psychobiology · 2026Article
- Variants of Callous-Unemotional Traits in Middle Childhood: An Investigation of Emotional Regulation, Externalizing Behaviors, and Psychosocial Risk Factors.Children (Basel, Switzerland) · 2025Article
- Respiratory Sinus Arrhythmia (RSA) Reactivity and Developmental Delay in the Preschool Years.Developmental psychobiology · 2025Article
- Latent Class Analysis of Prenatal Substance Exposure and Child Behavioral Outcomes.The Journal of pediatrics · 2023Article
- Latent profiles of children's autonomic nervous system reactivity early in life predict later externalizing problems.Developmental psychobiology · 2020Article
- Stress and parenting predict changes in adolescent respiratory sinus arrhythmia.Developmental psychobiology · 2019Article
- Approaches to modeling the development of physiological stress responsivity.Psychophysiology · 2018Article
- Cumulative risk exposure moderates the association between parasympathetic reactivity and inhibitory control in preschool-age children.Developmental psychobiology · 2018Article
- Sex Differences in the Contribution of Respiratory Sinus Arrhythmia and Trauma to Children's Psychopathology.Journal of psychopathology and behavioral assessment · 2017Article
- Intersections between cardiac physiology, emotion regulation and interpersonal warmth in preschoolers: Implications for drug abuse prevention from translational neuroscience.Drug and alcohol dependence · 2016Article
- Early deprivation and autonomic nervous system functioning in post-institutionalized children.Developmental psychobiology · 2016Article
- Variation in Parasympathetic Dysregulation Moderates Short-term Memory Problems in Childhood Attention-Deficit/Hyperactivity Disorder.Journal of abnormal child psychology · 2015Article
- A multilevel prediction of physiological response to challenge: Interactions among child maltreatment, neighborhood crime, endothelial nitric oxide synthase gene (eNOS), and GABA(A) receptor subunit alpha-6 gene (GABRA6).Development and psychopathology · 2015Article
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11 authors.
Funding
Abstract
Neurobehavioral disinhibition (ND) is a complex condition reflecting a wide range of problems involving difficulties with emotion regulation and behavior control. Respiratory sinus arrhythmia (RSA) is a physiological correlate of emotion regulation that has been studied in a variety of at-risk populations; however, there are no studies of RSA in children with ND. Data were drawn from a prospective longitudinal study of prenatal substance exposure that included 1,073 participants. Baseline RSA and RSA reactivity to an attention-demanding task were assessed at 3, 4, 5, and 6 years. ND was assessed at ages 8/9, 11, and 13/14 years via behavioral dysregulation and executive dysfunction composite measures. Greater exposure to early adversity was related to less RSA reactivity at 3 years, increases in RSA reactivity from ages 3 to 6 years, and increased behavioral dysregulation from ages 8/9 to 13/14. RSA reactivity was examined as a moderator of the association between early adversity and changes in ND. A significant Early Adversity × RSA Reactivity quadratic interaction revealed that children with decelerations in RSA reactivity exhibited increases in behavioral dysregulation, regardless of their exposure to early adversity. However, greater exposure to early adversity was related to greater increases in behavioral dysregulation, but only if children exhibited accelerations in RSA reactivity from ages 3 to 6 years. The results contribute to our understanding of how interactions across multiple levels of analysis contribute to the development of ND.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.