Evidence map›Paper›PMID 24909106›Full record

ArticleCurrent treatment options in neurology2014

Management of pediatric status epilepticus.

Nicholas S Abend, Tobias Loddenkemper

Open access · greenAbstract read
In one paragraph

Article in Current treatment options in neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Super-Refractory Status Epilepticus: A Therapeutic Challenge in Paediatrics.Journal of clinical and diagnostic research : JCDR · 2017
    Article
  5. Childhood epilepsies: What should a pediatrician know?Neurosciences (Riyadh, Saudi Arabia) · 2017
    Review
  6. Management of Status Epilepticus in Children.Journal of clinical medicine · 2016
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Nicholas S AbendDepartments of Neurology and Pediatrics, The Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, 3501 Civic Center Blvd., Philadelphia, PA, 19104, USA, ABEND@email.chop.edu.
Tobias Loddenkemper
Boston University · USUniversity of Pennsylvania · US

Funding

Non-convulsive seizures in critically ill children:physiology and outcomeK23NS076550 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI ABEND, NICHOLAS SCOTT · 2011 to 2015
$877k
NINDS NIH HHS K23 NS076550
6 · The paper itself

Abstract

opinion statementStatus epilepticus (SE) is a medical emergency consisting of persistent or recurring seizures without a return to baseline mental status. SE can be divided into subtypes based on seizure types and underlying etiologies. Management should be implemented rapidly and based on pre-determined care pathways. The aim is to terminate seizures while simultaneously identifying and managing precipitant conditions. Seizure management involves "emergent" treatment with benzodiazepines (lorazepam intravenously, midazolam intramuscularly, or diazepam rectally) followed by "urgent" therapy (phenytoin/fosphenytoin, phenobarbital, levetiracetam or valproate sodium). If seizures persist, "refractory" treatments include infusions of midazolam or pentobarbital. Prognosis is dependent on the underlying etiology and seizure persistence. This article reviews the current management strategies for pediatric convulsive SE.

Identifiers

PMID24909106
PMCPMC4110742
OpenAlexW1978839222

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.