Evidence map›Paper›PMID 24908035›Full record

ArticleThe Journal of chemical physics2014

Mixed confinement regimes during equilibrium confinement spectroscopy of DNA.

Damini Gupta, Julian Sheats, Abhiram Muralidhar, Jeremy J Miller, Derek E Huang, Sara Mahshid, Kevin D Dorfman, Walter Reisner

Abstract read
In one paragraph

Article in The Journal of chemical physics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Equilibrium structure and deformation response of 2D kinetoplast sheets.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  2. Article
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  4. Nanoplumbing with 2D Metamaterials.Small (Weinheim an der Bergstrasse, Germany) · 2019
    Article
  5. Measuring the wall depletion length of nanoconfined DNA.The Journal of chemical physics · 2018
    Article
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  15. Finite-size corrections for confined polymers in the extended de Gennes regime.Physical review. E, Statistical, nonlinear, and soft matter physics · 2015
    Article
  16. Article
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  20. Hydrodynamics of DNA confined in nanoslits and nanochannels.The European physical journal. Special topics · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Damini GuptaDepartment of Chemical Engineering and Materials Science, University of Minnesota - Twin Cities, 421 Washington Ave SE, Minneapolis, Minnesota 55455, USA.
Julian SheatsDepartment of Chemical Engineering and Materials Science, University of Minnesota - Twin Cities, 421 Washington Ave SE, Minneapolis, Minnesota 55455, USA.
Abhiram MuralidharDepartment of Chemical Engineering and Materials Science, University of Minnesota - Twin Cities, 421 Washington Ave SE, Minneapolis, Minnesota 55455, USA.
Jeremy J MillerDepartment of Chemical Engineering and Materials Science, University of Minnesota - Twin Cities, 421 Washington Ave SE, Minneapolis, Minnesota 55455, USA.
Derek E HuangDepartment of Chemical Engineering and Materials Science, University of Minnesota - Twin Cities, 421 Washington Ave SE, Minneapolis, Minnesota 55455, USA.
Sara MahshidPhysics Department, McGill University, 3600 rue University, Montreal, Quebec H3A 2T8, Canada.
Kevin D DorfmanDepartment of Chemical Engineering and Materials Science, University of Minnesota - Twin Cities, 421 Washington Ave SE, Minneapolis, Minnesota 55455, USA.
Walter ReisnerPhysics Department, McGill University, 3600 rue University, Montreal, Quebec H3A 2T8, Canada.

Funding

Dynamics of DNA Barcoding in NanochannelsR01HG006851 · NHGRI · UNIVERSITY OF MINNESOTA · PI DORFMAN, KEVIN D · 2013 to 2018
$2.1M
NHGRI NIH HHS R01 HG006851NHGRI NIH HHS R01-HG006851
6 · The paper itself

Abstract

We have used a combination of fluorescence microscopy experiments and Pruned Enriched Rosenbluth Method simulations of a discrete wormlike chain model to measure the mean extension and the variance in the mean extension of λ-DNA in 100 nm deep nanochannels with widths ranging from 100 nm to 1000 nm in discrete 100 nm steps. The mean extension is only weakly affected by the channel aspect ratio. In contrast, the fluctuations of the chain extension qualitatively differ between rectangular channels and square channels with the same cross-sectional area, owing to the "mixing" of different confinement regimes in the rectangular channels. The agreement between experiment and simulation is very good, using the extension due to intercalation as the only adjustable parameter.

Indexed as

DNAIntercalating AgentsNanostructuresNucleic Acid ConformationSpectrum AnalysisDNAIntercalating Agents

Identifiers

PMID24908035
PMCPMC4048444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.