ArticlePhysiological reports2014
Startle evoked movement is delayed in older adults: implications for brainstem processing in the elderly.
Article in Physiological reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
- Early Developmental Characterization of Gap-Induced Prepulse Inhibition and Habituation of Auditory Startle Response in a Fragile X Syndrome Mouse Model.Developmental neuroscience · 2026Article
- Inter- and intra- individual variability in audiovisual multisensory processes in healthy ageing.Aging brain · 2026Article
- Evidence for preserved insulin responsiveness in the aging rat brain.GeroScience · 2022Article
- Delays in the Reticulospinal System Are Associated With a Reduced Capacity to Learn a Simulated Feeding Task in Older Adults.Frontiers in neural circuits · 2021Article
- Aging changes in protective balance and startle responses to sudden drop perturbations.Journal of neurophysiology · 2019Article
- Aging effects of motor prediction on protective balance and startle responses to sudden drop perturbations.Journal of biomechanics · 2019Article
- Startle evokes nearly identical movements in multi-jointed, two-dimensional reaching tasks.Experimental brain research · 2019Article
- A Unifying Pathophysiological Account for Post-stroke Spasticity and Disordered Motor Control.Frontiers in neurology · 2019Article
- Neurophysiological analysis of the clinical pull test.Journal of neurophysiology · 2018Article
- Erratum.Physiological reports · 2017Article
- Foreknowledge of an impending startling stimulus does not affect the proportion of startle reflexes or latency of StartReact responses.Experimental brain research · 2017Article
- A broadband acoustic stimulus is more likely than a pure tone to elicit a startle reflex and prepared movements.Physiological reports · 2015Article
- Degraded expression of learned feedforward control in movements released by startle.Experimental brain research · 2015Article
- Responses to startling acoustic stimuli indicate that movement-related activation does not build up in anticipation of action.Journal of neurophysiology · 2015Article
- Responses to startling acoustic stimuli indicate that movement-related activation is constant prior to action: a replication with an alternate interpretation.Physiological reports · 2015Article
- Article
Corrections and comments
- Erratum issuedErratum.2017
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
Abstract
Little attention has been given to how age affects the neural processing of movement within the brainstem. Since the brainstem plays a critical role in motor control throughout the whole body, having a clear understanding of deficits in brainstem function could provide important insights into movement deficits in older adults. A unique property of the startle reflex is its ability to involuntarily elicit planned movements, a phenomenon referred to as startReact. The noninvasive startReact response has previously been used to probe both brainstem utilization and motor planning. Our objective was to evaluate deficits in startReact hand extension movements in older adults. We hypothesized that startReact hand extension will be intact but delayed. Electromyography was recorded from the sternocleidomastoid (SCM) muscle to detect startle and the extensor digitorum communis (EDC) to quantify movement onset in both young (24 ± 1) and older adults (70 ± 11). Subjects were exposed to a startling loud sound when prepared to extend their hand. Trials were split into those where a startle did (SCM+) and did not (SCM-) occur. We found that startReact was intact but delayed in older adults. SCM+ onset latencies were faster than SCM- trials in both the populations, however, SCM+ onset latencies were slower in older adults compared to young (Δ = 8 msec). We conclude that the observed age-related delay in the startReact response most likely arises from central processing delays within the brainstem.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.