ArticleGenome research2014
Methane yield phenotypes linked to differential gene expression in the sheep rumen microbiome.
Article in Genome research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 197 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
197 citing papers in PubMed, 434 citations in OpenAlex.
- Comparative metataxonomic analysis of total, viable, and active rumen microbial communities under methane-mitigated conditions.Environmental microbiome · 2026Article
- Methane emissions in beef cattle: A review of measurements and mitigation strategies.Veterinary and animal science · 2026Review
- Integrative analysis of rumen microbiota activity and host metabolism following methanogenesis inhibition in dairy cattle.Microbiology spectrum · 2026Article
- The Hungate1000 prokaryotic culture collection encodes a wide variety of bacteriocins.mSystems · 2026Article
- Blood-derived gene expression profiles associated with dietary microalgae oil intake and methane emission variation in lambs.BMC genomics · 2026Article
- Variations in methane emissions from dairy cows: associations with rumen microbial synergy and metabolic pathway divergence.Journal of animal science and biotechnology · 2026Article
- Effects of Replacing Whole-Crop Maize Silage withAnimals : an open access journal from MDPI · 2026Article
- Reliable enteric methane prediction from the cattle (Bos taurus) rumen microbiome.Communications biology · 2026Article
- Article
- Metagenomic analysis of fecal microbiomes reveals genetic potential for diverse hydrogen management strategies in marsupials.mSystems · 2026Article
- Effects of Licorice Stem and Leaf Semi-Dry Silage Instead of Alfalfa Hay on In Vitro Rumen Fermentation Characteristics and Dynamic Changes of Rumen Microbial Community in Holstein Cows.Veterinary sciences · 2026Article
- Exploring the link between ruminal methane production and physiological changes in Japanese Black cattle during fattening.Scientific reports · 2026Article
- Uncovering Major Structural and Functional Features of Methyl-Coenzyme M Reductase (MCR) fromInternational journal of molecular sciences · 2026Article
- Intracellular accumulation of hydrophobic 1,3-PDN inhibits methanogenesis in rumen methanogens.The ISME journal · 2026Article
- Understanding the influence of sward type and dairy cow breed on enteric methane emissions through investigation of the rumen microbiome.Frontiers in microbiology · 2026Article
- Using gnotobiotic ruminants to dissect host-microbe interactions for sustainable agriculture.Frontiers in microbiology · 2026Article
- Differences in prokaryotic and viral community between rumen and feces.Scientific reports · 2025Article
- Short- and long-term dietary supplementation as well as withdrawal of the enteric methane inhibitor 3-nitrooxypropanol reveal distinct effects on the rumen microbial community.Journal of animal science and biotechnology · 2025Article
- Gut microbiome plasticity and host resistance in response to ocean warming in sub-Antarctic sea urchins.BMC biology · 2025Article
- Methanogenesis inhibition remodels microbial fermentation and stimulates acetogenesis in ruminants.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
137 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ruminant livestock represent the single largest anthropogenic source of the potent greenhouse gas methane, which is generated by methanogenic archaea residing in ruminant digestive tracts. While differences between individual animals of the same breed in the amount of methane produced have been observed, the basis for this variation remains to be elucidated. To explore the mechanistic basis of this methane production, we measured methane yields from 22 sheep, which revealed that methane yields are a reproducible, quantitative trait. Deep metagenomic and metatranscriptomic sequencing demonstrated a similar abundance of methanogens and methanogenesis pathway genes in high and low methane emitters. However, transcription of methanogenesis pathway genes was substantially increased in sheep with high methane yields. These results identify a discrete set of rumen methanogens whose methanogenesis pathway transcription profiles correlate with methane yields and provide new targets for CH4 mitigation at the levels of microbiota composition and transcriptional regulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.