Evidence map›Paper›PMID 24906953›Full record

ReviewMolecular neurobiology2015

Gas sensing in nematodes.

M A Carrillo, E A Hallem

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular neurobiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Differential processing of a chemosensory cue across life stages sharing the same valence state inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Feeding state sculpts a circuit for sensory valence inProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  14. Terror in the dirt: Sensory determinants of host seeking in soil-transmitted mammalian-parasitic nematodes.International journal for parasitology. Drugs and drug resistance · 2018
    Review
  15. Mechanisms of host seeking by parasitic nematodes.Molecular and biochemical parasitology · 2016
    Review
  16. Adapt or avoid.eLife · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

M A CarrilloDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
E A Hallem

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nearly all animals are capable of sensing changes in environmental oxygen (O2) and carbon dioxide (CO2) levels, which can signal the presence of food, pathogens, conspecifics, predators, or hosts. The free-living nematode Caenorhabditis elegans is a powerful model system for the study of gas sensing. C. elegans detects changes in O2 and CO2 levels and integrates information about ambient gas levels with other internal and external cues to generate context-appropriate behavioral responses. Due to its small nervous system and amenability to genetic and genomic analyses, the functional properties of its gas-sensing microcircuits can be dissected with single-cell resolution, and signaling molecules and natural genetic variations that modulate gas responses can be identified. Here, we discuss the neural basis of gas sensing in C. elegans, and highlight changes in gas-evoked behaviors in the context of other sensory cues and natural genetic variations. We also discuss gas sensing in other free-living nematodes and parasitic nematodes, focusing on how gas-sensing behavior has evolved to mediate species-specific behavioral requirements.

Indexed as

Species SpecificityAnimalsCaenorhabditis elegansCarbon DioxideHumansNematodaOxygenTranscription FactorsCarbon DioxideOxygenTranscription Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.