Evidence map›Paper›PMID 24906834›Full record

ArticleEnvironmental science and pollution research international2014

Assessment of genotoxic effects of lead in occupationally exposed workers.

Srinivas Chinde, Monika Kumari, Kanapuram Rudrama Devi, Upadhyayula Suryanarayana Murty, Mohammed Fazlur Rahman, Srinivas Indu Kumari, Mohammed Mahboob, Paramjit Grover

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In one paragraph

Article in Environmental science and pollution research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Potential Antidote Against Lead Toxicity-A Review.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
  5. First Report of Mitochondrial DNA Copy Number Variation inAnimals : an open access journal from MDPI · 2023
    Article
  6. Article
  7. Article
  8. Assessment of Bone Turnover Biomarkers in Lead-Battery Workers with Long-Term Exposure to Lead.The international journal of occupational and environmental medicine · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Srinivas ChindeToxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad, Andhra Pradesh, 500007, India.
Monika Kumari
Kanapuram Rudrama Devi
Upadhyayula Suryanarayana Murty
Mohammed Fazlur Rahman
Srinivas Indu Kumari
Mohammed Mahboob
Paramjit Grover
Indian Institute of Chemical Technology · INOsmania University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genotoxicological effects in 200 lead acid storage battery recycling and manufacturing industry workers in Hyderabad along with matched 200 controls were studied. The genetic damage was determined by comet, micronucleus (MN), and chromosomal aberration (CA) test in peripheral blood lymphocytes (PBL). The MN test was also carried out in buccal epithelial cells (BECs). Pb in ambient air, blood Pb (B-Pb) concentrations, and hematological parameters were measured. The superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), glutathione peroxidase (GPx), and malondialdehyde (MDA) formed were also studied. The results of the present study showed that there was a statistically significant (P < 0.01) increase in mean percent tail DNA, frequency of CA, and MN in PBL as well as in BEC as compared to controls. Pb in ambient air and B-Pb concentrations were found to be significantly higher (P < 0.01). The hematocrit, hemoglobin, and red blood cell values were significantly lowered in Pb-exposed workers in comparison to controls. SOD, GPx, and CAT levels were significantly decreased while GSH and MDA levels increased in exposed group when compared to control group. The present study suggests that environmental health standards should be enforced to control Pb contamination from battery industries to reduce human health risk.

Indexed as

AdultAir Pollutants, OccupationalCatalaseChromosome AberrationsComet AssayDNA DamageElectric Power SuppliesEnvironmental MonitoringEpithelial CellsErythrocytesGlutathione PeroxidaseHumansIndiaLeadLymphocytesMaleAir Pollutants, OccupationalCatalaseGlutathione PeroxidaseLeadMalondialdehydeMutagensSuperoxide Dismutase

Identifiers

PMID24906834
OpenAlexW2058986652

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.