Trial reportBMC neurology2014
A task-oriented circuit training in multiple sclerosis: a feasibility study.
Trial report in BMC neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 21 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Task-oriented Circuit Class Training in Multiple Sclerosis Subjects
The Effect of a Functional Task-training Program Combined With Therapeutic Ultrasound on Pain, Strength, Gait Biomechanics and Functionality in Adults With Hip Osteoarthritis
The Effect of Task-Oriented Training on the Physical and Cognitive Functions in Patients With Multiple Sclerosis
Who cites it
21 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Effects of exercise on fatigue and quality of life in multiple sclerosis: a network meta-analysis and systematic review.Journal of neurology · 2025Pooled it
- Effects of Balance Exercise Interventions on Balance-Related Performance in People With Multiple Sclerosis: A Systematic Review and a Meta-Analysis of Randomized Controlled Trials.Neurorehabilitation and neural repair · 2024Pooled it
- Safety of exercise training in multiple sclerosis: An updated systematic review and meta-analysis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2023Pooled it
- Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions: a systematic review and meta-analysis of randomised controlled trials.Scientific reports · 2023Pooled it
- Exercise training improves participation in persons with multiple sclerosis: A systematic review and meta-analysis.Journal of sport and health science · 2022Pooled it
- Which exercise and behavioural interventions show most promise for treating fatigue in multiple sclerosis? A network meta-analysis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2021Pooled it
- Physical exercise improves quality of life, depressive symptoms, and cognition across chronic brain disorders: a transdiagnostic systematic review and meta-analysis of randomized controlled trials.Journal of neurology · 2021Pooled it
- Outcome measures used in trials on gait rehabilitation in multiple sclerosis: A systematic literature review.PloS one · 2021Pooled it
- Exercise therapy for fatigue in multiple sclerosis.The Cochrane database of systematic reviews · 2015Pooled it
- Feasibility and preliminary efficacy of different intensities of functional training in elderly type 2 diabetes patients with cognitive impairment: a pilot randomised controlled trial.BMC geriatrics · 2024Trial
- Intensive Circuit Class Therapy in Patients with Relapsing-Remitting Multiple Sclerosis.Journal of rehabilitation medicine · 2022Trial
- Task-oriented circuit training combined with aerobic training improves motor performance and balance in people with Parkinson's Disease.Acta neurologica Belgica · 2021Trial
- Effects of Task-Oriented Circuit Training on Dizziness, Vertigo Balance, Gait, and Quality of Life in Patients with Peripheral Vestibular Hypofunction: A Single-Blind, Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2026Article
- Investigation of the effect of task-oriented occupational therapy on daily living activity performance in chronic stroke patients.Pakistan journal of medical sciences · 2024Article
- Task-oriented exercise effects on walking and corticospinal excitability in multiple sclerosis: protocol for a randomized controlled trial.BMC sports science, medicine & rehabilitation · 2023Article
- Exercise Self-Efficacy and Fatigue as Predictors of Adherence to Home-Based Exercise Among Patients with Multiple Sclerosis.Patient preference and adherence · 2023Article
- Effects of Different Exercise Therapies on Balance Function and Functional Walking Ability in Multiple Sclerosis Disease Patients-A Network Meta-Analysis of Randomized Controlled Trials.International journal of environmental research and public health · 2022Review
- Important considerations for feasibility studies in physical activity research involving persons with multiple sclerosis: a scoping systematic review and case study.Pilot and feasibility studies · 2018Article
- Cerebellar Dysfunction in Multiple Sclerosis.Frontiers in neurology · 2017Review
- Monitoring Step Activity During Task-Oriented Circuit Training in High-Functioning Chronic Stroke Survivors: A Proof-of-Concept Feasibility Study.Annals of rehabilitation medicine · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to evaluate the safety, feasibility and preliminary effects of a high-intensity rehabilitative task-oriented circuit training (TOCT) in a sample of multiple sclerosis (MS) subjects on walking competency, mobility, fatigue and health-related quality of life (HRQoL).
methods24 MS subjects (EDSS 4.89 ± 0.54, 17 female and 7 male, 52.58 ± 11.21 years, MS duration 15.21 ± 8.68 years) have been enrolled and randomly assigned to 2 treatment groups: (i) experimental group received 10 TOCT sessions over 2 weeks (2 hours/each session) followed by a 3 months home exercise program, whereas control group did not receive any specific rehabilitation intervention. A feasibility patient-reported questionnaire was administered after TOCT. Functional outcome measures were: walking endurance (Six Minute Walk Test), gait speed (10 Meter Walk Test), mobility (Timed Up and Go test) and balance (Dynamic Gait Index). Furthermore, self-reported questionnaire of motor fatigue (Fatigue Severity Scale), walking ability (Multiple Sclerosis Walking Scale - 12) and health-related quality of life (Multiple Sclerosis Impact Scale - 29) were included. Subjects' assessments were delivered at baseline (T0), after TOCT (T1) and 3 months of home-based exercise program (T2).
resultsAfter TOCT subjects reported a positive global rating on the received treatment. At 3 months, we found a 58.33% of adherence to the home-exercise program. After TOCT, walking ability and health-related quality of life were improved (p < 0.05) with minor retention after 3 months. The control group showed no significant changes in any variables.
conclusionsThis two weeks high-intensity task-oriented circuit class training followed by a three months home-based exercise program seems feasible and safe in MS people with moderate mobility impairments; moreover it might improve walking abilities.
trial registrationNCT01464749.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.