Evidence map›Paper›PMID 24906200›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2014

Exploring strain-promoted 1,3-dipolar cycloadditions of end functionalized polymers.

Petr A Ledin, Nagesh Kolishetti, Manish S Hudlikar, Geert-Jan Boons

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Petr A LedinDepartment of Chemistry, University of Georgia, 140 Cedar Street, Athens, GA 30602 (USA); Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA, 30602 (USA).
Nagesh Kolishetti
Manish S Hudlikar
Geert-Jan Boons

Funding

Synthesis/Immunological Properties of Lewis AntigensR01CA088986 · NCI · UNIVERSITY OF GEORGIA (UGA) · PI BOONS, GEERT-JAN · 2002 to 2015
$4.6M
NCI NIH HHS R01 CA088986NCI NIH HHS R01CA088986
6 · The paper itself

Abstract

Strain-promoted 1,3-dipolar cycloaddition of cyclooctynes with 1,3-dipoles such as azides, nitrones, and nitrile oxides, are of interest for the functionalization of polymers. In this study, we have explored the use of a 4-dibenzocyclooctynol (DIBO)-containing chain transfer agent in reversible addition-fragmentation chain transfer polymerizations. The controlled radical polymerization resulted in well-defined DIBO-terminating polymers that could be modified by 1,3-dipolar cycloadditions using nitrones, nitrile oxides, and azides having a hydrophilic moiety. The self-assembly properties of the resulting block copolymers have been examined. The versatility of the methodology was further demonstrated by the controlled preparation of gold nanoparticles coated with the DIBO-containing polymers to produce materials that can be further modified by strain-promoted cycloadditions.

Indexed as

Click ChemistryCyclizationCycloaddition ReactionPolymerizationPolymersPolymersalkynescycloadditiongoldnanoparticlespolymerization

Identifiers

PMID24906200
PMCPMC4113408

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.