Izumo meets Juno: preventing polyspermy in fertilization.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

28 citing papers in PubMed.

1. Extracellular vesicles in bovine reproduction: their journey from gametogenesis to pregnancy.Frontiers in cell and developmental biology · 2026
   Review
2. TheBiomolecules · 2025
   Review
3. Spermatozoa lacking TEX51 display hypofertility and defects in morphology.Communications biology · 2025
   Article
4. Crossing the barrier or how regulation of ovastacin controls fertilization and translates into clinical phenotypes.iScience · 2025
   Review
5. No evidence for a direct extracellular interaction between human Fc receptor-like 3 (MAIA) and the sperm ligand IZUMO1.Science advances · 2024
   Article
6. Amniotic Mesenchymal-Derived Extracellular Vesicles and Their Role in the Prevention of Persistent Post-Breeding Induced Endometritis.International journal of molecular sciences · 2023
   Article
7. C11orf94/Frey is a key regulator for male fertility by controlling Izumo1 complex assembly.Science advances · 2022
   Article
8. The Importance of Gene Duplication and Domain Repeat Expansion for the Function and Evolution of Fertilization Proteins.Frontiers in cell and developmental biology · 2022
   Review
9. Molecular mechanisms and evolution of fertilization proteins.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2021
   Review
10. Expression, structure and function analysis of the sperm-oocyte fusion genes Juno and Izumo1 in sheep (Ovis aries).Journal of animal science and biotechnology · 2021
    Article
11. Extracellular vesicles and female reproduction.Journal of assisted reproduction and genetics · 2021
    Review
12. Role of Zinc (Zn) in Human Reproduction: A Journey from Initial Spermatogenesis to Childbirth.International journal of molecular sciences · 2021
    Review
13. Successful outcome of a pregnancy derived from premature ovulation in a gonadotropin-releasing hormone antagonist protocol: A case report.Clinical case reports · 2021
    Article
14. Thoughts on the popularity of ICSI.Journal of assisted reproduction and genetics · 2021
    Review
15. Find and fuse: Unsolved mysteries in sperm-egg recognition.PLoS biology · 2020
    Review
16. New advances and future directions in plant polyspermy.Molecular reproduction and development · 2020
    Review
17. Extracellular Vesicle Mediated Crosstalk Between the Gametes, Conceptus, and Female Reproductive Tract.Frontiers in veterinary science · 2020
    Review
18. Zinc sparks induce physiochemical changes in the egg zona pellucida that prevent polyspermy.Integrative biology : quantitative biosciences from nano to macro · 2017
    Article
19. Epigenetic reprogramming of the zygote in mice and men: on your marks, get set, go!Reproduction (Cambridge, England) · 2016
    Review
20. The molecular basis of fertilization (Review).International journal of molecular medicine · 2016
    Review

Corrections and comments

• Comment on
  Juno is the egg Izumo receptor and is essential for mammalian fertilization.2014

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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