Evidence map›Paper›PMID 24905988›Full record

ReviewNucleus (Austin, Tex.)

Nuclear positioning by actin cables and perinuclear actin: Special and general?

Sven Huelsmann, Nicholas H Brown

Open access · goldAbstract readReview
In one paragraph

Review in Nucleus (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Cell polarization: From epithelial cells to odontoblasts.European journal of cell biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Sven HuelsmannThe Gurdon Institute and Department of Physiology, Development, and Neuroscience; University of Cambridge; Cambridge, UK; Department of Biological and Environmental Science; University of Jyväskylä; Jyväskylä, Finland.
Nicholas H BrownThe Gurdon Institute and Department of Physiology, Development, and Neuroscience; University of Cambridge; Cambridge, UK.
Wellcome/Cancer Research UK Gurdon Institute · GB

Funding

Cancer Research UK C6946/A14492Wellcome Trust 086451Wellcome Trust 092096
6 · The paper itself

Abstract

Nuclear positioning is an important process during development and homeostasis. Depending on the affected tissue, mislocalized nuclei can alter cellular processes such as polarization, differentiation, or migration and lead ultimately to diseases. Many cells actively control the position of their nucleus using their cytoskeleton and motor proteins. We have recently shown that during Drosophila oogenesis, nurse cells employ cytoplasmic actin cables in association with perinuclear actin to position their nucleus. Here, we briefly summarize our work and discuss why nuclear positioning in nurse cells is specialized but the molecular mechanisms are likely to be more generally used.

Indexed as

ActinsAnimalsCell NucleusCytoskeletonHumansActinsactin cablesDrosophiladumpingfilaminLINC complexnuclear positioningnurse cellsperinuclear actin

Identifiers

PMID24905988
PMCPMC4133217
OpenAlexW2331360393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.