ArticleEpidemiology and psychiatric sciences2015
Degree of cognitive impairment and mortality: a 17-year follow-up in a community study.
Article in Epidemiology and psychiatric sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Can Physical Activity Reduce the Risk of Cognitive Decline in Apolipoprotein e4 Carriers? A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Differences across males and females in cognitive aging and mortality risk: a trajectory-based approach.GeroScience · 2026Article
- Cognitive trajectories in older adults and associated mortality and predictors.Social psychiatry and psychiatric epidemiology · 2025Article
- Role of cognitive impairment in predicting the long-term risk of all-cause mortality: a 20-year prospective cohort study in China.Archives of public health = Archives belges de sante publique · 2025Article
- VR Cognitive-based Intervention for Enhancing Cognitive Functions and Well-being in Older Adults with Mild Cognitive Impairment: Behavioral and EEG Evidence.Psychosocial intervention · 2025Article
- Exposure to indoor air pollution and the cognitive functioning of elderly rural women: a cross-sectional study using LASI data, India.BMC public health · 2022Article
- Similar mortality risk in incident cognitive impairment and dementia: Evidence from the ASPirin in Reducing Events in the Elderly (ASPREE) trial.Journal of the American Geriatrics Society · 2021Article
- Cognitive impairment and all-cause mortality among Chinese adults aged 80 years or older.Brain and behavior · 2021Article
- Cognitive Function and Mortality: Results from Kaunas HAPIEE Study 2006-2017.International journal of environmental research and public health · 2020Article
- Increasing Burden of Complex Multimorbidity Across Gradients of Cognitive Impairment.American journal of Alzheimer's disease and other dementias · 2017Article
- Staging cognitive impairment and incidence of dementia.Epidemiology and psychiatric sciences · 2016Article
- Functional measures, inflammatory markers and endothelin-1 as predictors of 360-day survival in centenarians.Age (Dordrecht, Netherlands) · 2015Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo test the hypothesis that cognitive impairment in older adults is associated with all-cause mortality risk and the risk increases when the degree of cognitive impairment augments; and then, if this association is confirmed, to report the population-attributable fraction (PAF) of mortality due to cognitive impairment.
methodA representative random community sample of individuals aged over 55 was interviewed, and 4557 subjects remaining alive at the end of the first year of follow-up were included in the analysis. Instruments used in the assessment included the Mini-Mental Status Examination (MMSE), the History and Aetiology Schedule (HAS) and the Geriatric Mental State (GMS)-AGECAT. For the standardised degree of cognitive impairment Perneczky et al's MMSE criteria were applied. Mortality information was obtained from the official population registry. Multivariate Cox proportional hazard models were used to test the association between MMSE degrees of cognitive impairment and mortality risk. We also estimated the PAF of mortality due to specific MMSE stages.
resultsCognitive impairment was associated with mortality risk, the risk increasing in parallel with the degree of cognitive impairment (Hazard ratio, HR: 1.18 in the 'mild' degree of impairment; HR: 1.29 in the 'moderate' degree; and HR: 2.08 in the 'severe' degree). The PAF of mortality due to severe cognitive impairment was 3.49%.
conclusionsA gradient of increased mortality-risk associated with severity of cognitive impairment was observed. The results support the claim that routine assessment of cognitive function in older adults should be considered in clinical practice.
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