Evidence map›Paper›PMID 24904957›Full record

ArticleEthnicity & health2015

Overweight, high blood pressure and impaired fasting glucose in Uyghur, Han, and Kazakh Chinese children and adolescents.

W L Yan, X S Li, Q Wang, Y D Huang, W G Zhang, X H Zhai, C C Wang, J H Lee

Abstract read
In one paragraph

Article in Ethnicity & health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 36 citations in OpenAlex.

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  7. Prediabetes in youth - mechanisms and biomarkers.The Lancet. Child & adolescent health · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

W L Yan *Department of Clinical Epidemiology, Children's Hospital of Fudan University, Shanghai 201102, China.
X S Li *The No.5 Hospital of Fudan University, 128 Ruili Road, Minhang District. Shanghai, China 200240.
Q WangDepartment of Epidemiology & Statistics, School of Public Health, Xinjiang Medical University, 393 Xinyi Road, Urumqi, Xinjiang, China 830011 (where study were carried out).
Y D HuangDepartment of Epidemiology & Statistics, School of Public Health, Xinjiang Medical University, 393 Xinyi Road, Urumqi, Xinjiang, China 830011 (where study were carried out).
W G ZhangDepartment of Epidemiology & Statistics, School of Public Health, Xinjiang Medical University, 393 Xinyi Road, Urumqi, Xinjiang, China 830011 (where study were carried out).
X H ZhaiDepartment of Epidemiology & Statistics, School of Public Health, Xinjiang Medical University, 393 Xinyi Road, Urumqi, Xinjiang, China 830011 (where study were carried out).
C C WangDepartment of Epidemiology & Statistics, School of Public Health, Xinjiang Medical University, 393 Xinyi Road, Urumqi, Xinjiang, China 830011 (where study were carried out).
J H LeeSergievsky Center, Taub Institute, and Department of Epidemiology, Columbia University, New York, NY, 10032 USA.
Xinjiang Medical University · CNChildren's Hospital of Fudan University · CNColumbia University · USFudan University · CN

Funding

Inferring phenogentic mechanisms in psychiatric and other complex traitsR01MH084995 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI TERWILLIGER, JOSEPH DOUGLAS · 2009 to 2012
$1.6M
NIMH NIH HHS R01 MH084995
6 · The paper itself

Abstract

objectivesTo investigate whether the levels of blood pressure and fasting glucose differ among Chinese children of three different ethnicities (i.e., Uyghurs, Kazakhs, and Hans) and whether the differences are explained by childhood obesity.

methodsA school-based cross-sectional study was conducted in a large three ethnic pediatric population (n = 6633), whose ages ranged from 7 to 18 years. Anthropometrics and blood pressure were measured using standard protocols. Fasting glucose was measured in a subset of children (n = 2295) who were randomly selected based on ethnicity and age. The age-sex stratified Chinese national cut-offs were used to define obesity and high blood pressure (HBP). The prevalence of HBP, impaired fasting glucose (IFG), mean levels of blood pressure, and glucose were compared among three ethnic groups.

results2142 Uyghurs, 2078 Han, and 1997 Kazakhs were analyzed. After adjusting for age and body mass index (BMI), the mean blood pressure for Uyghurs was on average, 2-4 mm Hg lower than those for Hans and Kazakhs. Kazakhs had the lowest mean fasting glucose compared with Hans and Uyghurs (4.5 vs. 5.0 vs. 4.8 mmol/L, respectively). The differences in blood pressure and fasting glucose persisted even after adjusting for age and BMI, and the differences among ethnic groups in blood pressure levels and fasting glucose levels were observed as early as 7-9 years of age.

conclusionsThe prevalence of HBP and IFG differed significantly among Uyghurs, Hans, and Kazakhs, and the ethnic differences observed in childhood were consistent with those observed in adults from the same region. While childhood obesity is a significant risk factor for hypertension and elevated glucose, the differences among ethnic groups were not explained by obesity alone.

Indexed as

AdolescentBlood GlucoseBlood PressureBody Mass IndexChildChinaCross-Sectional StudiesEthnicityFemaleHumansHypertensionKazakhstanMaleOverweightBlood Glucosechildren and adolescentsdiabetesethnic differencehypertensionobesity

Identifiers

PMID24904957
PMCPMC4258184
OpenAlexW2069581971

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.