ReviewFrontiers in cellular and infection microbiology2014
Phagosomal TLR signaling upon Borrelia burgdorferi infection.
Review in Frontiers in cellular and infection microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Endosome restricted human TLR1 polymorphism highlights a role for MyD88 in Pam3CSK4 detection.PloS one · 2026Article
- Characterizing the impact of intracutaneous dissemination on host responses duringFrontiers in immunology · 2026Article
- Article
- Global transcriptomic analysis of breast cancer and normal mammary epithelial cells infected with Borrelia burgdorferi.European journal of microbiology & immunology · 2023Article
- The Cdkn2a gene product p19 alternative reading frame (p19ARF) is a critical regulator of IFNβ-mediated Lyme arthritis.PLoS pathogens · 2022Article
- Epidemiologic, Clinical and Immunological Consequences of Co-Infections during Canine Leishmaniosis.Animals : an open access journal from MDPI · 2021Review
- Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation.BMC immunology · 2021Article
- Stimulated Immune Response by TruCultureFrontiers in cellular and infection microbiology · 2021Observational
- Immune Response toCurrent issues in molecular biology · 2021Article
- IL-26 mediated human cell activation and antimicrobial activity againstCurrent research in microbial sciences · 2020Article
- A multi-omic analysis reveals the regulatory role of CD180 during the response of macrophages to Borrelia burgdorferi.Emerging microbes & infections · 2018Article
- Human neuroglial cells internalize Borrelia burgdorferi by coiling phagocytosis mediated by Daam1.PloS one · 2018Article
- Primary Human Microglia Are Phagocytically Active and Respond toFrontiers in microbiology · 2018Article
- Isoforskolin downregulates proinflammatory responses induced byExperimental and therapeutic medicine · 2017Article
- Interaction of primary mast cells with Borrelia burgdorferi (sensu stricto): role in transmission and dissemination in C57BL/6 mice.Parasites & vectors · 2017Article
- MyD88 in Mycobacterium tuberculosis infection.Medical microbiology and immunology · 2017Review
- Infection with the Lyme disease pathogen suppresses innate immunity in mice with diet-induced obesity.Cellular microbiology · 2017Article
- The Potential of Omics Technologies in Lyme Disease Biomarker Discovery and Early Detection.Infectious diseases and therapy · 2017Review
- Cell Signaling Pathways That Regulate Antigen Presentation.Journal of immunology (Baltimore, Md. : 1950) · 2016Review
- The Putative Role of Viruses, Bacteria, and Chronic Fungal Biotoxin Exposure in the Genesis of Intractable Fatigue Accompanied by Cognitive and Physical Disability.Molecular neurobiology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Internalization and degradation of live Bb within phagosomal compartments of monocytes, macrophages and dendritic cells (DCs), allows for the release of lipoproteins, nucleic acids and other microbial products, triggering a broad and robust inflammatory response. Toll-like receptors (TLRs) are key players in the recognition of spirochetal ligands from whole viable organisms (i.e., vita-PAMPs). Herein we will review the role of endosomal TLRs in the response to the Lyme disease spirochete.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.