ArticleArchives of medical science : AMS2014
Advances in the diagnosis and management of diabetic distal symmetric polyneuropathy.
Article in Archives of medical science : AMS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- Reduced heart rate variability predicts incident diabetic polyneuropathy.Frontiers in endocrinology · 2026Article
- Review
- Screening for diabetic peripheral neuropathy in resource-limited settings.Diabetology & metabolic syndrome · 2023Review
- Exploring the molecular role of endostatin in diabetic neuropathy.Molecular biology reports · 2021Review
- Distal Symmetric Polyneuropathy Identification in Type 2 Diabetes Subjects: A Random Forest Approach.Healthcare (Basel, Switzerland) · 2021Article
- Article
- Evaluation of sural nerve automated nerve conduction study in the diagnosis of peripheral neuropathy in patients with type 2 diabetes mellitus.Archives of medical science : AMS · 2016Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Distal symmetric polyneuropathy (DSPN) is the most common chronic complication of diabetes mellitus. The pathogenesis of DSPN is not fully elucidated, but it is certainly multifactorial in nature and attributable to metabolic and microvessel disorders related to chronic hyperglycemia, diabetes duration, and several cardiovascular risk factors. Early diagnosis and appropriate management are extremely important, since up to 50% of DSPN cases may be asymptomatic, and patients are unaware of foot injury leading to foot ulcers and amputation. Simple, validated tests such as the Neuropathy Disability Score and/or Vibration Perception Threshold may be used to diagnose DSPN. Similarly, neurological dysfunction screening questionnaires should be used to assess the quality and severity of DSPN symptoms. Using both methods enables prediction of the prognosis of diabetic patients with DSPN. No causative treatment of DSPN is known, but the results of clinical trials indicate that several treatment options are highly effective in symptomatic treatment of painful DSPN. The appropriate treatment of DSPN may improve the outcome, preventing or delaying the development of numerous diabetic complications.
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