Evidence map›Paper›PMID 24904657›Full record

ArticleArchives of medical science : AMS2014

Hyperkalemia among hospitalized patients and association between duration of hyperkalemia and outcomes.

Jagadish Khanagavi, Tanush Gupta, Wilbert S Aronow, Tushar Shah, Jalaj Garg, Chul Ahn, Sachin Sule, Stephen Peterson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of medical science : AMS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 144 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jagadish KhanagaviDepartment of Medicine, Westchester Medical Center, New York Medical College, Valhalla, New York, USA.
Tanush GuptaDepartment of Medicine, Westchester Medical Center, New York Medical College, Valhalla, New York, USA.
Wilbert S AronowDivision of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, New York, USA.
Tushar ShahDepartment of Medicine, Westchester Medical Center, New York Medical College, Valhalla, New York, USA.
Jalaj GargDepartment of Medicine, Westchester Medical Center, New York Medical College, Valhalla, New York, USA.
Chul AhnDepartment of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Sachin SuleDepartment of Medicine, Westchester Medical Center, New York Medical College, Valhalla, New York, USA.
Stephen PetersonDepartment of Medicine, Westchester Medical Center, New York Medical College, Valhalla, New York, USA.
Westchester Medical Center · USNew York Medical College · USThe University of Texas Southwestern Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of the study was to investigate predictors of mortality in patients hospitalized with hyperkalemia. MATERIAL AND

methodsData among hospitalized patients with hyperkalemia (serum potassium ≥ 5.1 mEq/l) were collected. Patients with end-stage renal disease on dialysis were excluded.

resultsOf 15,608 hospitalizations, 451 (2.9%) episodes of hyperkalemia occurred in 408 patients. In patients with hyperkalemia, chronic kidney disease, hypertension, diabetes, coronary artery disease and heart failure were common comorbidities. Acute kidney injury (AKI) and metabolic acidosis were common metabolic abnormalities, and 359 patients (88%) were on at least one drug associated with hyperkalemia. Mean duration to resolution of hyperkalemia was 12 ±9.9 h. Nonsteroidal anti-inflammatory drugs (HR = 1.59), highest potassium level (HR = 0.61), tissue necrosis (HR = 0.61), metabolic acidosis (HR = 0.77), and AKI (HR = 0.77) were significant independent determinants of duration prior to hyperkalemia resolution. Tissue necrosis (OR = 4.55), potassium supplementation (OR = 5.46), metabolic acidosis (OR = 4.84), use of calcium gluconate for treatment of hyperkalemia (OR = 4.62), AKI (OR = 3.89), and prolonged duration of hyperkalemia (OR = 1.06) were significant independent predictors of in-hospital mortality.

conclusionsTissue necrosis, potassium supplementation, metabolic acidosis, calcium gluconate for treatment of hyperkalemia, AKI and prolonged duration of hyperkalemia are independent predictors of in-hospital mortality.

Indexed as

drug-induced hyperkalemiain-hospital mortalitypotassium supplementsprolonged hyperkalemia

Identifiers

PMID24904657
PMCPMC4042045
OpenAlexW1973622329

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.