Evidence map›Paper›PMID 24904583›Full record

ReviewFrontiers in immunology2014

Immune responses to inhalant Mammalian allergens.

François Hentges, Cathy Léonard, Karthik Arumugam, Christiane Hilger

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
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  12. Article
  13. Article
  14. Review
  15. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

François HentgesLaboratory of Immunogenetics and Allergology, CRP-Santé , Luxembourg , Luxembourg.
Cathy LéonardLaboratory of Immunogenetics and Allergology, CRP-Santé , Luxembourg , Luxembourg.
Karthik ArumugamLaboratory of Retrovirology, CRP-Santé , Luxembourg , Luxembourg.
Christiane HilgerLaboratory of Immunogenetics and Allergology, CRP-Santé , Luxembourg , Luxembourg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Europe and the USA, at least one person in four is exposed every day to inhalant allergens of mammalian origin, a considerable number is regularly exposed for professional reasons and almost everyone is occasionally exposed to inhalant allergens from pets or domestic animals. The production of IgE to these inhalant allergens, often complicated by asthma and rhinitis, defines the atopic status. However, the immune response to these allergens largely imprints the cellular immune compartment and also drives non-IgE humoral immune responses in the allergic and non-allergic population. During the recent years, it has become clear that IgE antibodies recognize mammalian allergens that belong to three protein or glycoprotein families: the secretoglobins, the lipocalins, and the serum albumins. In this article, we review the humoral and cellular immune responses to the major members of these families and try to define common characteristics and also distinctive features.

Indexed as

albuminallergencellular responsecross-reactivityIgE responselipocalinsecretoglobin

Identifiers

PMID24904583
PMCPMC4033121

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.