Evidence map›Paper›PMID 24904250›Full record

ArticleJournal of applied crystallography2014

A new view on crystal harvesting.

Joseph R Luft, Thomas D Grant, Jennifer R Wolfley, Edward H Snell

Abstract read
In one paragraph

Article in Journal of applied crystallography, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Using sound pulses to solve the crystal-harvesting bottleneck.Acta crystallographica. Section D, Structural biology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joseph R LuftHauptman-Woodward Medical Research Institute, 700 Ellicott Street, Buffalo, NY 14203, USA.
Thomas D GrantHauptman-Woodward Medical Research Institute, 700 Ellicott Street, Buffalo, NY 14203, USA.
Jennifer R WolfleyHauptman-Woodward Medical Research Institute, 700 Ellicott Street, Buffalo, NY 14203, USA.
Edward H SnellHauptman-Woodward Medical Research Institute, 700 Ellicott Street, Buffalo, NY 14203, USA ; Department of Structural Biology, SUNY Buffalo, 700 Ellicott Street, Buffalo, NY 14203, USA.

Funding

Enabling Technologies to Macromolecular CrystallizationR01GM100494 · NIGMS · HAUPTMAN-WOODWARD MEDICAL RESEARCH INST · PI LUFT, JOSEPH · 2011 to 2014
$1.9M
Development of an Expert Crystallization Knowledge SystemR01GM088396 · NIGMS · HAUPTMAN-WOODWARD MEDICAL RESEARCH INST · PI SNELL, EDWARD H · 2010 to 2014
$1.7M
NIGMS NIH HHS R01 GM088396NIGMS NIH HHS R01 GM100494
6 · The paper itself

Abstract

X-ray crystallography typically requires the mounting of crystals, which can make the sample difficult to manipulate when it is small and the microscope objective is close to the crystallization plate. By simply moving the objective to the bottom of a clear crystallization plate (inverting the normal view), crystals were able to be manipulated and harvested from wells having a 0.9 mm diameter and 5.0 mm depth. The mounting system enabled the structural solution of the 187 amino acid N-terminal domain of

Indexed as

crystal imagingcrystal mountinghigh throughput

Identifiers

PMID24904250
PMCPMC4038804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.