Evidence map›Paper›PMID 24904119›Full record

ReviewBlood2014

A tour through the transcriptional landscape of platelets.

Sebastian Schubert, Andrew S Weyrich, Jesse W Rowley

Abstract readReview
In one paragraph

Review in Blood, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 127 citations in OpenAlex.

  1. Article
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sebastian SchubertThe Molecular Medicine Program and.
Andrew S WeyrichThe Molecular Medicine Program and Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT.
Jesse W RowleyThe Molecular Medicine Program and Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT.
University of Utah · US

Funding

Translational Research Skills Development CoreU54HL112311 · NHLBI · UNIVERSITY OF UTAH · PI WEYRICH, ANDREW S, ZIMMERMAN, GUY A. · 2012 to 2016
$12.9M
TRANSLATIONAL EVENTS IN PLATELETSR01HL066277 · NHLBI · UNIVERSITY OF UTAH · PI WEYRICH, ANDREW S · 2001 to 2012
$3.8M
The Platelet Metabolome in ObesityK01GM103806 · NIGMS · UNIVERSITY OF UTAH · PI ROWLEY, JESSE · 2012 to 2016
$802k
NHLBI NIH HHS 1U54 HL112311-01NHLBI NIH HHS 2R01 HL066277-11NHLBI NIH HHS R01 HL066277NHLBI NIH HHS U54 HL112311NIGMS NIH HHS 1K01 GM103806-01NIGMS NIH HHS K01 GM103806
6 · The paper itself

Abstract

The RNA code found within a platelet and alterations of that code continue to shed light onto the mechanistic underpinnings of platelet function and dysfunction. It is now known that features of messenger RNA (mRNA) in platelets mirror those of nucleated cells. This review serves as a tour guide for readers interested in developing a greater understanding of platelet mRNA. The tour provides an in-depth and interactive examination of platelet mRNA, especially in the context of next-generation RNA sequencing. At the end of the expedition, the reader will have a better grasp of the topography of platelet mRNA and how it impacts platelet function in health and disease.

Indexed as

Transcription, GeneticAnimalsBlood PlateletsHumansPlatelet ActivationRNA, MessengerRNA, Messenger

Identifiers

PMID24904119
PMCPMC4110657
OpenAlexW1977991745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.