ArticleJournal of the American Heart Association2014
Patterns of care quality and prognosis among hospitalized ischemic stroke patients with chronic kidney disease.
Article in Journal of the American Heart Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Central and peripheral arterial diseases in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.Kidney international · 2021Guideline
- Renal Function and Efficacy of Remote Ischemic Conditioning in Acute Moderate Ischemic Stroke: A Post Hoc Analysis of RICAMIS Trial.Brain and behavior · 2025Trial
- Association between blood urea nitrogen levels and mortality in critical acute ischemic stroke patients.Scientific reports · 2025Article
- Renal function and efficacy of dual antiplatelet vs. alteplase in minor stroke: aFrontiers in neurology · 2025Article
- Three-month functional outcomes of acute ischemic stroke in patients with chronic renal function impairment.PloS one · 2025Article
- Chronic Kidney Disease and Cerebrovascular Pathology: Incidence and Functional Outcomes in Riga East University Hospital.Medicina (Kaunas, Lithuania) · 2024Article
- Association of Renal Impairment with Clinical Outcomes Following Endovascular Therapy in Acute Basilar Artery Occlusion.Clinical interventions in aging · 2024Observational
- Low serum magnesium is associated with poor functional outcome in acute ischemic stroke or transient ischemic attack patients.CNS neuroscience & therapeutics · 2023Article
- Influence of renal impairment on neurologic outcomes following mechanical thrombectomy in acute vertebrobasilar stroke.Neuroradiology · 2022Article
- Impact of multimorbidity on risk and outcome of stroke: Lessons from chronic kidney disease.International journal of stroke : official journal of the International Stroke Society · 2021Article
- Renal Function-Dependent Associations of Statins with Outcomes of Ischemic Stroke.Journal of atherosclerosis and thrombosis · 2021Article
- Adherence to American Heart Association/American Stroke Association Clinical Performance Measures in a Peruvian Neurological Reference Institute.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2020Article
- Current Trends Featuring the Bridge Between Stroke and End-Stage Renal Disease: A Review.Cureus · 2020Review
- Post-Stroke Depression and Estimated Glomerular Filtration Rate: A Prospective Stroke Cohort.Neuropsychiatric disease and treatment · 2020Article
- Processes of Care Associated With Risk of Mortality and Recurrent Stroke Among Patients With Transient Ischemic Attack and Nonsevere Ischemic Stroke.JAMA network open · 2019Article
- Article
- Stroke and Chronic Kidney Disease: Epidemiology, Pathogenesis, and Management Across Kidney Disease Stages.Seminars in nephrology · 2015Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRelatively little is known about the quality of care and outcomes for hospitalized ischemic stroke patients with chronic kidney disease (CKD). We examined quality of care and in-hospital prognoses among patients with CKD in the Get With The Guidelines-Stroke (GWTG-Stroke) program METHODS AND
resultsWe analyzed 679 827 patients hospitalized with ischemic stroke from 1564 US centers participating in the GWTG-Stroke program between January 2009 and December 2012. Use of 7 predefined ischemic stroke performance measures, composite "defect-free" care compliance, and in-hospital mortality were examined based on glomerular filtration rate (GFR) categorized as a dichotomous (+CKD as <60) or rank-ordered variable: normal (≥ 90), mild (≥ 60 to <90), moderate (≥ 30 to <60), severe (≥ 15 to <30), and kidney failure (<15 or dialysis). There were 236 662 (35%) ischemic stroke patients with CKD. Patients with severe renal dysfunction or failure were significantly less likely to receive guideline-based therapies. Compared with patients with normal kidney function (≥ 90), those with CKD (adjusted OR 0.91 [95% CI: 0.89 to 0.92]), moderate dysfunction (adjusted OR 0.94 [95% CI: 0.92 to 0.97]), severe dysfunction (adjusted OR 0.80 [95% CI: 0.77 to 0.84]), or failure (adjusted OR 0.72 [95% CI: 0.68 to 0.0.76]), were less likely to receive 100% defect-free care measure compliance. Inpatient mortality was higher for patients with CKD (adjusted odds ratio 1.44 [95% CI: 1.40 to 1.47]), and progressively rose with more severe renal dysfunction.
conclusionsDespite higher in-hospital mortality rates, ischemic stroke patients with CKD, especially those with greater severity of renal dysfunction, were less likely to receive important guideline-recommended therapies.
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