ArticleBehavior research methods2015
When the test of mediation is more powerful than the test of the total effect.
Article in Behavior research methods, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
54 citing papers in PubMed.
- Effectiveness and Mechanisms of a Digital Mindfulness-Based Intervention for Subthreshold to Clinical Insomnia Symptoms in Pregnant Women: Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- Mediators of a randomized controlled trial of a preventive intervention for youth of parents with depressive disorders.Journal of consulting and clinical psychology · 2025Trial
- The Differential Relation of Emotional, Physical, and Sexual Abuse Histories to Antidepressant Treatment Remission and Persistence of Anhedonia in Major Depression: A CAN-BIND-1 Report.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2023Trial
- Using Novel Approaches to Evaluate Behavioral Interventions: Overlooked Significant HIV Prevention Effects in the HPTN 015 Project EXPLORE.Journal of acquired immune deficiency syndromes (1999) · 2021Trial
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- Trial
- Identifying the active ingredients of a behavioral activation-based digital single-session intervention targeting depression.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Obstructive sleep apnea mediates the association between body mass index and metabolic dysfunction-associated steatotic liver disease in patients with obesity.Hepatology international · 2026Article
- Maternal depression across childhood and offspring young adult depression and anxiety: Testing adolescent emotion dynamics as transdiagnostic mechanisms.JCPP advances · 2026Article
- The Myokine Irisin Represents an Indirect Pathway Linking Exercise to Hippocampal Subfields Relevant to Alzheimer's Disease and Neurogenesis.Aging cell · 2026Article
- Negative affect mediates the association between nightly sleep disturbance and next-day binge eating.Appetite · 2026Article
- Prefrontal Structural Asymmetry Mediates Body Mass Index and Treatment Response in Major Depressive Disorder.Depression and anxiety · 2026Article
- Examining the mechanisms linking Dark Triad traits to OCB through LMX and political skill: a comparative study of managerial and non-managerial levels.Frontiers in psychology · 2026Article
- Stressor-Evoked Brain Activity, Cardiovascular Reactivity, and Subclinical Atherosclerosis in Midlife Adults.Journal of the American Heart Association · 2025Article
- Examining pathways between structural stigma and tobacco use: a comparison among young adults living in the United States by sexual orientation and gender identity.International journal for equity in health · 2025Article
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- No association between markers of systemic inflammation and endothelial dysfunction with Alzheimer's disease progression: a longitudinal study.GeroScience · 2025Article
- Practical challenges in mediation analysis: a guide for applied researchers.Health services & outcomes research methodology · 2025Article
- Clinical trials with mechanism evaluation of intervention(s): mind the power and sample size calculation.Trials · 2024Article
- Applying a synergistic mindsets intervention to an esports context.Royal Society open science · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Although previous research has studied power in mediation models, the extent to which the inclusion of a mediator will increase power has not been investigated. To address this deficit, in a first study we compared the analytical power values of the mediated effect and the total effect in a single-mediator model, to identify the situations in which the inclusion of one mediator increased statistical power. The results from this first study indicated that including a mediator increased statistical power in small samples with large coefficients and in large samples with small coefficients, and when coefficients were nonzero and equal across models. Next, we identified conditions under which power was greater for the test of the total mediated effect than for the test of the total effect in the parallel two-mediator model. These results indicated that including two mediators increased power in small samples with large coefficients and in large samples with small coefficients, the same pattern of results that had been found in the first study. Finally, we assessed the analytical power for a sequential (three-path) two-mediator model and compared the power to detect the three-path mediated effect to the power to detect both the test of the total effect and the test of the mediated effect for the single-mediator model. The results indicated that the three-path mediated effect had more power than the mediated effect from the single-mediator model and the test of the total effect. Practical implications of these results for researchers are then discussed.
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