Evidence map›Paper›PMID 24903659›Full record

ArticlePediatric radiology2014

Accuracy of abdominal ultrasound and MRI for detection of Crohn disease and ulcerative colitis in children.

Manon L W Ziech, Thalia Z Hummel, Anne M J B Smets, Rutger A J Nievelstein, Cristina Lavini, Matthan W A Caan, Aart J Nederveen, Joris J T H Roelofs, Shandra Bipat, Marc A Benninga and 2 more

Abstract readComparative StudyEvaluation Study
PubMed Publisher
In one paragraph

Article in Pediatric radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. The Role of Intestinal Ultrasonography in Children with Inflammatory Bowel Disease.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Sonographic evaluation of a surgically created pouch.Abdominal radiology (New York) · 2023
    Review
  10. Review
  11. Review
  12. Article
  13. MRI of perianal fistulas in Crohn's disease.Acta bio-medica : Atenei Parmensis · 2020
    Article
  14. Article
  15. Article
  16. Comparison of Conventional Ultrasound and Contrast Enhanced Magnetic Resonance (MR) Enterography in Evaluation Patients with Crohn's Disease.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2018
    Article
  17. Diagnostic performance of PET/MR in the evaluation of active inflammation in Crohn disease.American journal of nuclear medicine and molecular imaging · 2018
    Article
  18. Article
  19. Role of ultrasound in colorectal diseases.World journal of gastroenterology · 2016
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Manon L W ZiechAcademic Medical Center, Department of Radiology, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands, m.l.ziech@amc.uva.nl.
Thalia Z Hummel
Anne M J B Smets
Rutger A J Nievelstein
Cristina Lavini
Matthan W A Caan
Aart J Nederveen
Joris J T H Roelofs
Shandra Bipat
Marc A Benninga
Angelika Kindermann
Jaap Stoker
Academic Medical Center · NLEmma Kinderziekenhuis · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoscopy is currently the primary diagnostic technique for inflammatory bowel disease (IBD) in children.

objectiveTo assess the accuracy of US and dynamic contrast-enhanced MRI for diagnosing inflammatory bowel disease and for distinguishing Crohn disease and ulcerative colitis in comparison to a reference standard. MATERIALS AND

methodsConsecutive children with suspected IBD underwent diagnostic workup including ileocolonoscopy and upper gastrointestinal endoscopy as the reference standard, abdominal US, and MR enterography and colonography at 3 T. The protocol included a dynamic contrast-enhanced 3-D sequence. Sensitivity, specificity and kappa values were calculated for one ultrasonographer and two MRI observers.

resultsWe included 28 children (15 boys) with mean age 14 years (range 10-17 years). The diagnosis was IBD in 23 children (72%), including 12 with Crohn disease, 10 with ulcerative colitis and 1 with indeterminate colitis. For the diagnosis of inflammatory bowel disease the sensitivity was 55% for US and 57% (both observers) for MR entero- and colonography, and the specificity was 100% for US and 100% (observer 1) and 75% (observer 2) for MR entero- and colonography. Combined MRI and US had sensitivity and specificity of 70% and 100% (observer 1) and 74% and 80% (observer 2), respectively. With the addition of a dynamic contrast-enhanced MR sequence, the sensitivity increased to 83% and 87%. US and MRI could only distinguish between Crohn disease and ulcerative colitis when terminal ileum lesions were present.

conclusionUS and MR entero- and colonography have a high accuracy for diagnosing inflammatory bowel disease in children but cannot be used to distinguish Crohn disease and ulcerative colitis.

Indexed as

AbdomenAdolescentChildColitis, UlcerativeCrohn DiseaseDiagnosis, DifferentialFemaleHumansMagnetic Resonance ImagingMaleReproducibility of ResultsSensitivity and SpecificityUltrasonography

Identifiers

PMID24903659
OpenAlexW1969340115

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.