Evidence map›Paper›PMID 24903165›Full record

ArticleMagnetic resonance in medicine2015

Real-time active MR-tracking of metallic stylets in MR-guided radiation therapy.

Wei Wang, Charles L Dumoulin, Akila N Viswanathan, Zion T H Tse, Alireza Mehrtash, Wolfgang Loew, Isaiah Norton, Junichi Tokuda, Ravi T Seethamraju, Tina Kapur and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. External Hardware and Sensors, for Improved MRI.Journal of magnetic resonance imaging : JMRI · 2023
    Review
  4. Article
  5. MR-Tracked Deflectable Stylet for Gynecologic Brachytherapy.IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division · 2022
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Design and Fabrication of MR-Tracked Metallic Stylet for Gynecologic Brachytherapy.IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division · 2016
    Article
  11. Article
  12. Magnetic Resonance-guided Active Catheter Tracking.Magnetic resonance imaging clinics of North America · 2015
    Review
  13. Magnetic Resonance Sequences and Rapid Acquisition for MR-Guided Interventions.Magnetic resonance imaging clinics of North America · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Wei WangRadiology, Brigham and Women's Hospital, Boston, Massachusetts, USA; Radiation Oncology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Charles L Dumoulin
Akila N Viswanathan
Zion T H Tse
Alireza Mehrtash
Wolfgang Loew
Isaiah Norton
Junichi Tokuda
Ravi T Seethamraju
Tina Kapur
Antonio L Damato
Robert A Cormack
Ehud J Schmidt
Brigham and Women's Hospital · USCincinnati Children's Hospital Medical Center · USSiemens Healthcare (United States) · USUniversity of Georgia · US

Funding

Image Guided Therapy Center - Ultrasound-based sensor system for the monitoring of COVID-19 patientsP41EB015898 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI TEMPANY, CLARE M · 2012 to 2021
$18.9M
ULTRASOUND THERAPY DELIVERY THROUGH INTACT SKULLU41RR019703 · NCRR · BRIGHAM AND WOMEN'S HOSPITAL · PI JOLESZ, FERENC A · 2005 to 2009
$17.2M
IMAGE GUIDED THERAPY CENTERP41RR019703 · NCRR · BRIGHAM AND WOMEN'S HOSPITAL · PI JOLESZ, FERENC A · 2010 to 2011
$8.6M
MR Image Guided Gynecologic BrachytherapyR21CA167800 · NCI · JOHNS HOPKINS UNIVERSITY · PI VISWANATHAN, AKILA · 2013 to 2014
$394k
Endorectal Prostate MRI w/Tetrahedron Tracking; Better Cancer DelineationR21CA158987 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI SCHMIDT, EHUD JERUHAM · 2012 to 2013
$356k
NCI NIH HHS 1R21CA158987-01A1NCI NIH HHS R21 CA158987NCI NIH HHS R21 CA 167800NCI NIH HHS R21 CA167800NCRR NIH HHS P41 RR019703NCRR NIH HHS U41 RR019703NIBIB NIH HHS P41 EB015898
6 · The paper itself

Abstract

purposeTo develop an active MR-tracking system to guide placement of metallic devices for radiation therapy.

methodsAn actively tracked metallic stylet for brachytherapy was constructed by adding printed-circuit micro-coils to a commercial stylet. The coil design was optimized by electromagnetic simulation, and has a radio-frequency lobe pattern extending ∼5 mm beyond the strong B0 inhomogeneity region near the metal surface. An MR-tracking sequence with phase-field dithering was used to overcome residual effects of B0 and B1 inhomogeneities caused by the metal, as well as from inductive coupling to surrounding metallic stylets. The tracking system was integrated with a graphical workstation for real-time visualization. The 3 Tesla MRI catheter-insertion procedures were tested in phantoms and ex vivo animal tissue, and then performed in three patients during interstitial brachytherapy.

resultsThe tracking system provided high-resolution (0.6 × 0.6 × 0.6 mm(3) ) and rapid (16 to 40 frames per second, with three to one phase-field dithering directions) catheter localization in phantoms, animals, and three gynecologic cancer patients.

conclusionThis is the first demonstration of active tracking of the shaft of metallic stylet in MR-guided brachytherapy. It holds the promise of assisting physicians to achieve better targeting and improving outcomes in interstitial brachytherapy.

Indexed as

ArtifactsFiducial MarkersMetalsAnimalsBrachytherapyChickensComputer GraphicsComputer SimulationElectromagnetic FieldsEquipment DesignFemaleGenital Neoplasms, FemaleImage EnhancementImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMetalsactive MR-trackingmetallic devicephase-field ditheringradiation therapy

Identifiers

PMID24903165
PMCPMC4257908
OpenAlexW2158749722

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.