Evidence map›Paper›PMID 24903137›Full record

ReviewDer Internist2014

[Age and osteoporosis. Effects of aging on osteoporosis, the diagnostics and therapy].

F Jakob, L Seefried, M Schwab

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Internist, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. The link between osteoporosis and cardiovascular diseases: a review of shared mechanisms, risk factors, and therapeutic approaches.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Review
  7. Article
  8. Article
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  11. Review
  12. How relevant is lumbar bone mineral density for the stability of symphyseal implants? A biomechanical cadaver study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Article
  13. Osteoporosis among Postmenopausal Women in Jordan: A National Cross-Sectional Study.International journal of environmental research and public health · 2022
    Article
  14. Article
  15. Biomedical reports · 2018
    Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

F JakobOrthopädische Klinik, Zentrum für Muskuloskelettale Forschung, Universität Würzburg, Brettreichstr. 11, 97074, Würzburg, Deutschland, f-jakob.klh@uni-wuerzburg.de.
L Seefried
M Schwab
University of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoporosis is an age-associated disease, which is influenced by genetic, epigenetic and environmental factors.

aimThis article examines the evidence for specific aspects in osteoporosis diagnosis and management in higher age groups. MATERIAL AND

methodsThe study was based on extraction of data from literature databases and from the guidelines of the "Dachverband Osteologie" (DVO, Governing Body for Osteology).

resultsAge is a high risk factor for osteoporosis. Vitamin D insufficiency and reduced calcium absorption are common in the elderly. Loss of bone and muscle develop in a vicious circle of immobilization caused by underlying diseases. In addition deficits in cognition and coordination promote falls and fragility fractures. Clinical risk assessment including geriatric test batteries is recommended in all women > 70 and men > 80 years of age. Specific medication is indicated if the 10-year fracture risk exceeds 30 %, where in women > 75 and in men > 85 years of age bone density measurement can be relinquished. There is good evidence for the efficacy of antiosteoporotic medication even for the elderly. Prevention of falls requires multimodal management to enhance muscle power and coordination. It is essential to improve underlying cardiovascular, pulmonary and neurological diseases while critically evaluating the necessity of medication that boosts the risk of falls and fractures. There is good evidence for age and disease-adapted exercise programs such as Tai-Chi. Treating osteoporosis reduces the fracture risk, improves the quality of life, maintains independence and decreases mortality.

conclusionTreating osteoporosis in the elderly is strongly recommended. Multimodal management and medication according to guidelines can be very successful, given that interdisciplinary and geriatric concepts consider the specific needs of the elderly population.

Indexed as

Accidental FallsAgedAged, 80 and overAge DistributionBone Density Conservation AgentsCombined Modality TherapyExercise TherapyGeriatric AssessmentGermanyHumansIncidenceOsteoporosisOsteoporotic FracturesPrevalenceRisk FactorsTreatment OutcomeBone Density Conservation Agents

Identifiers

PMID24903137
OpenAlexW1832705355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.