Trial reportObesity surgery2014
Effect of carbohydrate restriction in patients with hyperinsulinemic hypoglycemia after Roux-en-Y gastric bypass.
Trial report in Obesity surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07580079 (Anakinra for the Treatment of Recurrent Postprandial Hypoglycemia After Total Gastrectomy in a Patient With End-Stage Renal Disease), which is not on this map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Anakinra for the Treatment of Recurrent Postprandial Hypoglycemia After Total Gastrectomy in a Patient With End-Stage Renal Disease
Who cites it
19 citing papers in PubMed, 47 citations in OpenAlex.
- A single dose trial of mizagliflozin for the treatment of postbariatric hypoglycemia.Journal of the Endocrine Society · 2026Article
- Post-bariatric Hypoglycemia Management: A Gulf Cooperation Council Consensus Statement.Journal of the Endocrine Society · 2026Article
- β-Cell Mass in Individuals With and Without Postbariatric Hypoglycemia After Roux-en-Y Gastric Bypass.Diabetes · 2025Article
- Bariatric surgery and diabetes: Current challenges and perspectives.World journal of diabetes · 2024Review
- The Impact of Cholecystectomy in Patients with Post-Bariatric Surgery Hypoglycemia.Obesity surgery · 2024Article
- Society for Endocrinology guidelines for the diagnosis and management of post-bariatric hypoglycaemia.Endocrine connections · 2024Review
- An Imbalance of Pathophysiologic Factors in Late Postprandial Hypoglycemia Post Bariatric Surgery: A Narrative Review.Obesity surgery · 2023Review
- Long-term Outcomes of Transoral Outlet Reduction (TORe) for Dumping Syndrome and Weight Regain After Roux-en-Y Gastric Bypass.Obesity surgery · 2023Article
- Beyond diabetes remission a step further: Post bariatric surgery hypoglycemia.World journal of diabetes · 2022Article
- Digital Solutions to Diagnose and Manage Postbariatric Hypoglycemia.Frontiers in nutrition · 2022Review
- International consensus on the diagnosis and management of dumping syndrome.Nature reviews. Endocrinology · 2020Review
- Insights from the Impact of Meal Composition on Glucose Profile Towards Post-bariatric Hypoglycemia Management.Obesity surgery · 2020Article
- Roux en Y gastric bypass hypoglycemia resolves with gastric feeding or reversal: Confirming a non-pancreatic etiology.Molecular metabolism · 2018Article
- Hyperinsulinemic hypoglycemia after gastric bypass surgery: what's up and what's down?International journal of obesity (2005) · 2017Review
- Medical nutrition therapy for post-bariatric hypoglycemia: practical insights.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2017Review
- Continuous Glucose Monitoring After Gastric Bypass to Evaluate the Glucose Variability After a Low-Carbohydrate Diet and to Determine Hypoglycemia.Obesity surgery · 2016Article
- Impact of Carbohydrate Content and Glycemic Load on Postprandial Glucose After Roux-en-Y Gastric Bypass.Obesity surgery · 2016Article
- Insulin response to oral stimuli and glucose effectiveness increased in neuroglycopenia following gastric bypass.Obesity (Silver Spring, Md.) · 2015Article
- Diagnosis and Management of Post-Bariatric Hypoglycemia.Journal of the American Board of Family Medicine : JABFMReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHyperinsulinemic hypoglycemia is a rare complication of Roux-en-Y gastric bypass (RYGB) surgery. Meals with a high carbohydrate (carb) content and high glycemic index (GI) may provoke these hypoglycemic attacks. The aim of this study is to assess the effects of reducing meal carb content and GI on glycemic responses in patients with post-RYGB hypoglycemia.
methodsFourteen patients with post-RYGB hypoglycemia underwent two meal tests: a mixed meal test (MMT) with a carb content of 30 g and a meal test with the low GI supplement, Glucerna SR 1.5® (Glucerna meal test (GMT)). Plasma glucose and serum insulin levels were measured for a period of 6 h.
resultsPeak glucose levels were reached at T 30 during GMT and at T 60 during MMT, and they were 1.5 ± 0.3 mmol/L lower during GMT than during MMT (7.5 ± 0.4 vs 9.0 ± 0.4 mmol/L, P < 0.005). GMT induced the most rapid rise in plasma insulin: at T 30 plasma, insulin was 30.7 ± 8.5 mU/L higher during GMT than during MMT (P < 0.005). None of the carb-restricted meals induced post-prandial hypoglycemia.
conclusionA 30-g carb-restricted meal may help to prevent post-prandial hypoglycemia in patients with post-RYGB hypoglycemia. The use of a liquid, low GI, supplement offers no additional advantage.
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