ArticleCirculation. Cardiovascular imaging2014
Left atrial passive emptying function determined by cardiac magnetic resonance predicts atrial fibrillation recurrence after pulmonary vein isolation.
Article in Circulation. Cardiovascular imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- The presence of atrial fibrillation in Takotsubo cardiomyopathy is predictive of mortality: Systematic review and meta-analysis.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2019Pooled it
- An echocardiographic model for predicting the recurrence of paroxysmal atrial fibrillation after circumferential pulmonary vein ablation.Clinical cardiology · 2021Trial
- Cardiac magnetic resonance imaging in the assessment of cardiac injury and toxicity from cancer-related chemotherapy.Pediatric radiology · 2025Review
- Non-Invasive Prediction of Atrial Fibrosis Using a Regression Tree Model of Mean Left Atrial Voltage.Biomedicines · 2025Article
- Ablation of Ventricular and Atrial Arrhythmias in the Era of Cardiac Magnetic Resonance.Echocardiography (Mount Kisco, N.Y.) · 2025Review
- Progress in the application of cardiac magnetic resonance to predict recurrence of atrial fibrillation after catheter ablation: A systematic review andInternational journal of cardiology. Heart & vasculature · 2025Review
- Genetic Determinants of Left Atrial Function Are Associated With Stroke.Journal of the American Heart Association · 2024Article
- Investigating the importance of left atrial compliance on fluid dynamics in a novel mock circulatory loop.Scientific reports · 2024Article
- Reference data for left ventricular filling and atrial function in children using cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Article
- 3-Dimensional Strain Analysis of Hypertrophic Cardiomyopathy: Insights From the NHLBI International HCM Registry.JACC. Cardiovascular imaging · 2023Article
- The association of left atrial mechanics with left ventricular morphology in patients with hypertrophic cardiomyopathy: a cardiac magnetic resonance study.Polish journal of radiology · 2023Article
- Cardiac magnetic resonance diastolic indices correlate with ventricular filling pressures in pediatric heart transplant recipients.Pediatric transplantation · 2022Article
- From Left Atrial Dimension to Curved M-Mode Speckle-Tracking Images: Role of Echocardiography in Evaluating Patients with Atrial Fibrillation.Reviews in cardiovascular medicine · 2022Review
- Association of left atrial strain by cardiovascular magnetic resonance with recurrence of atrial fibrillation following catheter ablation.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022Article
- Influence of Sex-Based Differences in Cardiac Phenotype on Atrial Fibrillation Recurrence in Patients Undergoing Pulmonary Vein Isolation.Frontiers in cardiovascular medicine · 2022Article
- Diagnostic value of left atrial strain in pediatric hypertrophic cardiomyopathy with normal maximum left atrial volume index: preliminary cardiac magnetic resonance study.Pediatric radiology · 2021Article
- Intramyocardial Triglycerides Among Women With vs Without HIV: Hormonal Correlates and Functional Consequences.The Journal of clinical endocrinology and metabolism · 2019Article
- Distinct Subgroups in Hypertrophic Cardiomyopathy in the NHLBI HCM Registry.Journal of the American College of Cardiology · 2019Observational
- Individualised Approaches for Catheter Ablation of AF: Patient Selection and Procedural Endpoints.Arrhythmia & electrophysiology review · 2019Review
- Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAlthough pulmonary vein isolation has become a mainstream therapy for selected patients with atrial fibrillation (AF), late recurrent AF is common and its risk factors remain poorly defined. The purpose of our study was to test the hypothesis that reduced left atrial passive emptying function (LAPEF) as determined by cardiac magnetic resonance has a strong association with late recurrent AF after pulmonary vein isolation. METHODS AND
resultsThree hundred forty-six patients with AF referred for cardiac magnetic resonance pulmonary vein mapping before pulmonary vein isolation were included. Maximum LA volumes (VOLmax) and volumes before atrial contraction (VOLbac) were measured; LAPEF was calculated as (VOLmax-VOLbac)/VOLmax×100. Kaplan-Meier curves were constructed to determine late recurrent AF stratified by LAPEF quintile. Cox proportional hazards regression was used to adjust for known markers of recurrence. During a median follow-up of 27 months, 124 patients (35.8%) experienced late recurrent AF. Patients with recurrence were more likely to have nonparoxysmal AF (75.8% versus 51.4%; P<0.01), higher mean VOLmax (60.2 versus 52.8 mL/m(2); P<0.01), and lower mean LAPEF (19.1% versus 26.0%; P<0.01). Patients in the lowest LAPEF quintile were at highest risk of developing recurrent AF (2-year recurrence for lowest versus highest: 60.5% versus 17.3%; P<0.01). After adjusting for known predictors of recurrence, patients with low LAPEF remained significantly more likely to recur (hazard ratio for lowest versus highest quintile, 3.92; 95% confidence interval, 2.01-7.65).
conclusionsWe found a strong association between LAPEF and recurrent AF after pulmonary vein isolation that persisted after multivariable adjustment.
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