ArticleMarine drugs2014
Effects of long chain fatty acid synthesis and associated gene expression in microalga Tetraselmis sp.
Article in Marine drugs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 69 citations in OpenAlex.
- Effects of nitrate limitation on the metabolome ofCurrent research in microbial sciences · 2025Article
- Microalgae as a potential raw material for plant-based seafood alternatives: A comprehensive review.Food science & nutrition · 2024Review
- Bioactivity and Digestibility of MicroalgaeNutrients · 2023Review
- Evaluation of halophilic microalgae isolated from Rabigh Red Sea coastal area for biodiesel production: Screening and biochemical studies.Saudi journal of biological sciences · 2022Article
- Bioprospecting Indigenous Marine Microalgae for Polyunsaturated Fatty Acids Under Different Media Conditions.Frontiers in bioengineering and biotechnology · 2022Article
- Highly Valuable Polyunsaturated Fatty Acids from Microalgae: Strategies to Improve Their Yields and Their Potential Exploitation in Aquaculture.Molecules (Basel, Switzerland) · 2021Review
- Intestinal anti-inflammatory activity of Ulva ohnoi oil in DSS-induced experimental mouse model.Scientific reports · 2021Article
- Integrated algal and oil palm biorefinery as a model system for bioenergy co-generation with bioproducts and biopharmaceuticals.Bioresources and bioprocessing · 2021Review
- The carbon partitioning of glucose and DIC in mixotrophic, heterotrophic and photoautotrophic cultures of Tetraselmis suecica.Biotechnology letters · 2021Article
- Biochemical profiling of three indigenousBiotechnology reports (Amsterdam, Netherlands) · 2020Article
- High-Quality Draft Genome Sequence of the Green AlgaMicrobiology resource announcements · 2019Article
- Microalgae for High-Value Products Towards Human Health and Nutrition.Marine drugs · 2019Review
- Marine Natural Products from Microalgae: An -Omics Overview.Marine drugs · 2019Review
- New molecular insights on the response of the green alga Tetraselmis suecica to nitrogen starvation.Scientific reports · 2019Article
- Bioengineered Plants Can Be a Useful Source of Omega-3 Fatty Acids.BioMed research international · 2017Review
- Enhanced lipid and biomass production by a newly isolated and identified marine microalga.Lipids in health and disease · 2016Article
- How Very-Long-Chain Fatty Acids Could Signal Stressful Conditions in Plants?Frontiers in plant science · 2016Article
- Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the depletion of global fish stocks, caused by high demand and effective fishing techniques, alternative sources for long chain omega-3 fatty acids are required for human nutrition and aquaculture feeds. Recent research has focused on land-based cultivation of microalgae, the primary producers of omega-3 fatty acids in the marine food web. The effect of salinity on fatty acids and related gene expression was studied in the model marine microalga, Tetraselmis sp. M8. Correlations were found for specific fatty acid biosynthesis and gene expression according to salinity and the growth phase. Low salinity was found to increase the conversion of C18:4 stearidonic acid (SDA) to C20:4 eicosatetraenoic acid (ETA), correlating with increased transcript abundance of the Δ-6-elongase-encoding gene in salinities of 5 and 10 ppt compared to higher salinity levels. The expression of the gene encoding β-ketoacyl-coenzyme was also found to increase at lower salinities during the nutrient deprivation phase (Day 4), but decreased with further nutrient stress. Nutrient deprivation also triggered fatty acids synthesis at all salinities, and C20:5 eicosapentaenoic acid (EPA) increased relative to total fatty acids, with nutrient starvation achieving a maximum of 7% EPA at Day 6 at a salinity of 40 ppt.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.