Evidence map›Paper›PMID 24901537›Full record

ReviewChemical reviews2014

Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs).

Francois-Xavier Theillet, Andres Binolfi, Tamara Frembgen-Kesner, Karan Hingorani, Mohona Sarkar, Ciara Kyne, Conggang Li, Peter B Crowley, Lila Gierasch, Gary J Pielak and 3 more

Abstract readReview
In one paragraph

Review in Chemical reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 210 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
210citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

210 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Non-Fickian diffusion within assemblies of the intrinsically disordered protein β-casein.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  13. Article
  14. Article
  15. In situ NMR and integrative proteomics reveal the interaction signature of serum α-synuclein.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  16. Review
  17. Article
  18. Computational and Experimental Approaches and Applications of Biological NMR.Advances in experimental medicine and biology · 2026
    Review
  19. Article
  20. Article

150 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Francois-Xavier TheilletDepartment of NMR-supported Structural Biology, In-cell NMR Laboratory, Leibniz Institute of Molecular Pharmacology (FMP Berlin) , Robert-Roessle Strasse 10, 13125 Berlin, Germany.
Andres Binolfi
Tamara Frembgen-Kesner
Karan Hingorani
Mohona Sarkar
Ciara Kyne
Conggang Li
Peter B Crowley
Lila Gierasch
Gary J Pielak
Adrian H Elcock
Anne Gershenson
Philipp Selenko

Funding

PEPTIDE CONFORMATIONS &INTERACTIONS WITH MEMBRANESR01GM027616 · NIGMS · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI GIERASCH, LILA M · 1985 to 2015
$5.3M
CHEMISTRY-BIOLOGY INTERFACE PREDOCTORAL TRAINING GRANTST32GM008515 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI THOMPSON, LYNMARIE K. · 1995 to 2020
$4.3M
Modeling a cellular protein homeostasis networkR01GM101644 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI GIERASCH, LILA M, POWERS, EVAN THOMAS · 2013 to 2016
$1.6M
Molecular Simulations of Folding & Association in Physiological EnvironmentsR01GM087290 · NIGMS · UNIVERSITY OF IOWA · PI ELCOCK, ADRIAN HAMILTON · 2009 to 2017
$1.6M
Post-Reductionist Protein Folding: Determining the In-cell Folding Energy LandscaR01GM094848 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI GERSHENSON, ANNE, GIERASCH, LILA M · 2010 to 2013
$1.3M
Molecular Simulations of Cotranslational FoldingR01GM099865 · NIGMS · UNIVERSITY OF IOWA · PI ELCOCK, ADRIAN HAMILTON · 2012 to 2015
$1.0M
NIGMS NIH HHS R01 GM027616NIGMS NIH HHS R01GM027616NIGMS NIH HHS R01 GM087290NIGMS NIH HHS R01 GM094848NIGMS NIH HHS R01GM094848NIGMS NIH HHS R01 GM099865NIGMS NIH HHS R01 GM101644NIGMS NIH HHS R01GM101644NIGMS NIH HHS T32 GM008515NIGMS NIH HHS T32 GM08515
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell Physiological PhenomenaAnimalsCellsHumansIntrinsically Disordered ProteinsProtein ConformationIntrinsically Disordered Proteins

Identifiers

PMID24901537
PMCPMC4095937

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.